There have been ten clinical trials on the use of inhaled Cannabis in cancer patients that can be divided into two groups. In one group, four small studies assessed antiemetic activity but each explored a different patient population and chemotherapy regimen. One study demonstrated no effect, the second study showed a positive effect versus placebo, the report of the third study did not provide enough information to characterize the overall outcome as positive or neutral. Consequently, there are insufficient data to provide an overall level of evidence assessment for the use of Cannabis for chemotherapy-induced N/V. Apparently, there are no published controlled clinical trials on the use of inhaled Cannabis for other cancer-related or cancer treatment–related symptoms.
Also high in fiber, hemp seeds are more digestible than any other high-protein food, including meat, cheese, eggs, human milk, or cows’ milk. They’re high in antioxidants, and minerals like iron, zinc and copper as well as calcium, magnesium, potassium, carotene, thiamin (vitamin B1), riboflavin (vitamin B2), vitamin B6 and vitamin E. If that’s not enough, there’s also chlorophyll, sulfur, phosphorus, phospholipids, and phytosterols.
The etymology is uncertain but there appears to be no common Proto-Indo-European source for the various forms of the word; the Greek term kánnabis is the oldest attested form, which may have been borrowed from an earlier Scythian or Thracian word. Then it appears to have been borrowed into Latin, and separately into Slavic and from there into Baltic, Finnish, and Germanic languages. Following Grimm's law, the "k" would have changed to "h" with the first Germanic sound shift, after which it may have been adapted into the Old English form, hænep. However, this theory assumes that hemp was not widely spread among different societies until after it was already being used as a psychoactive drug, which Adams and Mallory (1997) believe to be unlikely based on archaeological evidence. Barber (1991) however, argued that the spread of the name "kannabis" was due to its historically more recent drug use, starting from the south, around Iran, whereas non-THC varieties of hemp are older and prehistoric. Another possible source of origin is Assyrian qunnabu, which was the name for a source of oil, fiber, and medicine in the 1st millennium BC.
Scientists in Europe and North America concluded that hemp seed is an excellent source of nutrition. Numerous anecdotal incidences cited improvements in a wide range of acute and chronic conditions such as rapid healing of skin lesions and relief from flu, inflammation, and allergies. The benefits were attributed to the presence of rich source of the EFAs linoleic and alpha-linolenic acid, and their respective biologic metabolites, GLA and stearidonic acid.9
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
Because of its high THC-content, in most parts of the world, including the US, Marijuana is illegal. Seeing the massive economical and medicinal benefits that Marijuana can provide, some countries and states in the US have legalized Marijuana. As the political landscape changes, hopefully more will follow, but as of now, Marijuana is generally illegal.
The 2014 Farm Bill included a section to allow for universities and state departments of agriculture to begin cultivating industrial hemp for purposes of research, provided that the growing and cultivating of industrial hemp is allowed under state law. Industrial hemp is defined by SB 263 as all parts and varieties of the plant cannabis sativa L that contain a delta-9 tetrahydrocannabinol (THC) concentration of no more than 0.3 percent on a dry weight basis.
Pain management improves a patient’s quality of life throughout all stages of cancer. Through the study of cannabinoid receptors, endocannabinoids, and synthetic agonists and antagonists, the mechanisms of cannabinoid-induced analgesia have been analyzed.[Level of evidence:1iC] The CB1 receptor is found in the central nervous system (CNS) and in peripheral nerve terminals. CB2 receptors are located mainly in peripheral tissue and are expressed in only low amounts in the CNS. Whereas only CB1 agonists exert analgesic activity in the CNS, both CB1 and CB2 agonists have analgesic activity in peripheral tissue.[48,49]
Separate levels of evidence scores are assigned to qualifying human studies on the basis of statistical strength of the study design and scientific strength of the treatment outcomes (i.e., endpoints) measured. The resulting two scores are then combined to produce an overall score. An overall level of evidence score cannot be assigned to cannabinoids because there has been insufficient clinical research. For an explanation of possible scores and additional information about levels of evidence analysis of CAM treatments for people with cancer, refer to Levels of Evidence for Human Studies of Integrative, Alternative, and Complementary Therapies.
Although always sold at a premium price, hemp clothing has a natural appeal to a sector of the population. Hemp clothes are resistant to abrasion, but are typically abrasive. However, appropriate processing and blending with other natural fibers has significantly improved the “feel” of the product, and in China hemp textiles indistinguishable from fine linens in texture are available. Weaving of hemp fibers into textiles and apparel is primarily done in China, Hungary, Romania, Russia, and the Ukraine. Processing costs are higher for industrial hemp because the fibers vary from the standard specifications for fiber length and diameter established for the equipment used in most textile and apparel factories, necessitating the use of specialty machines. The North American hemp apparel industry today is based on fiber, yarn, and fabrics imported from Eastern Europe and China. The extraction technology and spinning facilities, to say nothing of much lower labor costs, make it very difficult for the potential development of a hemp textile industry in North America. The fact that spinning facilities for natural fibers are so concentrated in China is making it increasingly difficult to competitively produce hemp fabrics elsewhere. This of course lessens the value-added future of growing hemp for a potential textile industry in North America. It is possible, however, that new technologies could change this situation, and especially in the EU development is underway to establish a fledgling domestic hemp textile industry. In addition to textiles used in clothing, coarser woven cloth (canvas) is used for upholstery, bags, sacks, and tarpaulins. There is very little effort in North America to produce such woven products, and non-woven material (Fig. 15) can be more easily produced. Hempline in Ontario, the first firm to grow hemp for commercial purposes in North America since the second word war (starting with experimental cultivation in 1994), is the exception, and is concerned with production of fiber for upholstery and carpeting.
Hemp crops are tall, have thick foliage, and can be planted densely, and thus can be grown as a smother crop to kill tough weeds. Using hemp this way can help farmers avoid the use of herbicides, gain organic certification, and gain the benefits of crop rotation. However, due to the plant's rapid and dense growth characteristics, some jurisdictions consider hemp a prohibited and noxious weed, much like Scotch Broom.
In Europe and Asia, hemp farming has been conducted for millennia. Although most countries ceased growing hemp after the second word war, some didn’t, including France, China, Russia, and Hungary, so that essential knowledge of how to grow and process hemp was maintained. When commercial hemp cultivation resumed in Canada in 1997, many farmers undertook to grow the crop without appreciating its suitability for their situation, or for the hazards of an undeveloped market. Hemp was often grown on farms with marginal incomes in the hopes that it was a savior from a downward financial spiral. The myth that hemp is a wonder crop that can be grown on any soil led some to cultivate on soils with a history of producing poor crops; of course, a poor crop was the result.
Understanding the mechanism of cannabinoid-induced analgesia has been increased through the study of cannabinoid receptors, endocannabinoids, and synthetic agonists and antagonists. Cannabinoids produce analgesia through supraspinal, spinal, and peripheral modes of action, acting on both ascending and descending pain pathways. The CB1 receptor is found in both the central nervous system (CNS) and in peripheral nerve terminals. Similar to opioid receptors, increased levels of the CB1 receptor are found in regions of the brain that regulate nociceptive processing. CB2 receptors, located predominantly in peripheral tissue, exist at very low levels in the CNS. With the development of receptor-specific antagonists, additional information about the roles of the receptors and endogenous cannabinoids in the modulation of pain has been obtained.[43,44]
Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
Cannabis is frequently used among Sufis – the mystical interpretation of Islam that exerts strong influence over local Muslim practices in Bangladesh, India, Indonesia, Turkey, and Pakistan. Cannabis preparations are frequently used at Sufi festivals in those countries. Pakistan's Shrine of Lal Shahbaz Qalandar in Sindh province is particularly renowned for the widespread use of cannabis at the shrine's celebrations, especially its annual Urs festival and Thursday evening dhamaal sessions - or meditative dancing sessions.
Anybody can apply to grow industrial hemp except one who has been convicted of a felony for controlled substance in the past 10 years. Anyone who has been issued a hemp license can grow on the approved growing areas indicated on their application. Licensed industrial hemp can be grown anywhere, indoor or outdoor. The research pilot program allows for any size growing area, from large acre lots to small garden sizes. There are no zoning requirements for a hemp license.
Jump up ^ Morales, Paula; Hurst, Dow P.; Reggio, Patricia H. (2017). "Molecular Targets of the Phytocannabinoids: A Complex Picture". In Kinghorn, A. Douglas; Falk, Heinz; Gibbons, Simon; Kobayashi, Jun'ichi. Phytocannabinoids: Unraveling the Complex Chemistry and Pharmacology of Cannabis sativa. Progress in the Chemistry of Organic Natural Products. 103. Springer International Publishing. pp. 103–131. doi:10.1007/978-3-319-45541-9_4. ISBN 978-3-319-45539-6. PMC 5345356. PMID 28120232.
Based on world production of fibers in 1999, about 54.5% was synthetic (of which 60.3% was polyester), 42.9% was plant fiber (of which 78.5% was cotton), and 2.6% was wool (Karus 2000). In addition to cotton, flax is the only other significant plant fiber crop grown in temperate regions of the world (kenaf has received some enthusiastic backing in the southern US in recent years, but is most cheaply produced in India, Bangladesh, and China). Flax held 2.7% of the world plant fiber market in 1999, while hemp had only 0.3% (Karus 2000). Hemp fiber can potentially replace other biological fibers in many applications, but also, as noted below, can sometimes compete with minerals such as glass fiber and steel. As forests diminish, cultivation of annual plants as fiber sources is likely to increase. While crop residues like cereal straw will probably supply much of the need, specialty fiber plants such as hemp also have potential. The four conditions that will need to be met are (after Bolton 1995): (1) the material should be produced at a large enough scale; (2) the price should be low enough; (3) the fiber characteristics should be adequate for the end use; and (4) proven technology should be available for the processing of the new raw material. Of these criteria only point 3 is adequately met at this time for hemp in North America, but this is to be expected in a crop that has only begun to be cultivated after an absence of many years.
Each and every bottle is grown and processed with the same standards as the last guaranteeing quality and assuring potency. Made from CBD rich hemp flower sun grown in Oregon and MCT oil, Rosebud is proud to be a Vegan, Gluten Free, Non-GMO, Organic, and Sustainably Processed CO2 extract. Choose between our three potencies: 350mg, 700mg and 1000mg.
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We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
To this point, CBD oil has existed in a kind of liminal space— at once an illegal drug, a legal medication, and some kind of “dietary” supplement. It’s possible this could change in the coming years, however. GW Pharmaceuticals, a U.K.-based firm, has developed a “pure CBD” medication called Epidiolex that has shown promising test results. It is currently on a fast-track to receive FDA clearance. For some patients, Epidiolex could be a miracle cure. This summer, in Wired magazine, writer Fred Vogelstein chronicled his family’s own struggles to find an effective treatment for his son’s epilepsy—including experiments with hemp oil— and the immense hurdles they overcame to gain access to Epidiolex prior to its FDA approval. The drug could be for sale on pharmacy shelves in the near future, though exactly how near is hard to say.
Two studies examined the effects of oral delta-9-THC on cancer pain. The first, a double-blind, placebo-controlled study involving ten patients, measured both pain intensity and pain relief. It was reported that 15 mg and 20 mg doses of the cannabinoid delta-9-THC were associated with substantial analgesic effects, with antiemetic effects and appetite stimulation.
Everybody has different medical needs, because of this Medix CBD hemp oil tinctures are available in different dosages ranging from 100mg – 4,500mg per bottle. The reason for such a large difference in CBD concentrations between the lowest strength bottle and the highest strength bottle is because we offer a vast and wide selection of CBD hemp oil tinctures to meet the needs of people with different medical goals.
Unfortunately due to strict FDA regulations I am unable to make claims on our products based on your specific needs, I can however say that CBD is a natural anti-inflammatory and could assist. I can also share our top selling products in each category. Please view the links below:http://cbdoilreview.org/product/elixinol-cbd-oil-extract-x-pen-1000mg/http://cbdoilreview.org/product/endoca-hemp-oil-drops-1500mg/http://cbdoilreview.org/product/elixinol-hemp-oil-drops-regular-300mg/http://cbdoilreview.org/product/elixinol-cbd-hemp-oil-capsules-900mg/https://cbdoilreview.org/product/vape-bright-starter-pack-200-mg/This is also a great link to some pages that you may find helpful https://cbdoilreview.org/cbd-cannabidiol/
"Right now, any claims and dosing recommendations by any company making a CBD product for the medical marijuana market is purely anecdotal," he says. "Asking 100 people who use your product whether they feel better isn't real science. The products on the market are also different from what was used in the scientific studies that they are basing their claims upon. If a study found an anti-anxiety effect when dosing humans with synthetic CBD, that doesn't mean that your CBD oil that contains 18 percent CBD is going to reduce anxiety. It might even have the opposite effect."
Industrial hemp is a versatile agricultural plant which could one day be a valuable crop option for Pennsylvania farmers. The Commonwealth of Pennsylvania has taken some important steps toward making that a reality. Following Governor Wolf’s signing of the Industrial Hemp Research Act, Number 92 in 2016, the Pennsylvania Department of Agriculture’s Industrial Hemp Research Pilot Program started issuing permits for research & growth of industrial hemp in 2017. Pennsylvania’s industrial hemp legislation was sparked by the passage of the 2014 Farm Bill, which gave federal permission for institutions of higher education or state Departments of Agriculture to research the cultivation and marketing of industrial hemp. As part of Pennsylvania’s Research Pilot Program, industrial hemp was legally grown in the Commonwealth after an 80 years hiatus. The Department of Agriculture has issued 35 research permits in the last two years to institutions of higher education and to farmers, business or individuals in contract with the Department to participate in the research of industrial hemp cultivation and marketing in Pennsylvania. In 2018, 35 research permits were issued to researchers, who cultivated industrial hemp in 25 Pennsylvania counties.
Edible cannabis, however, is quickly making up ground as a go-to method for consuming medical marijuana. Indeed, some states with legal medical marijuana laws still forbid smoking marijuana. Instead, medical forms of the drug are only available in pill or capsule form. Oils and tinctures, which are made from extracting cannabinoids from herbaceous material, are also commonly prescribed in the form of cannabis edibles.
If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.
The importation and movement of hemp seeds and plants is restricted under federal law. According to the Statement of Principles on Industrial Hemp (81 Federal Register (FR) 53395) issued by the U.S. Department of Agriculture, U.S. Drug Enforcement Administration, and U.S. Food and Drug Administration, "industrial hemp plants and seeds may not be transported across State lines." For more information, contact the U.S. Drug Enforcement Administration.
The leaves, stems, flower buds and extracts from the marijuana plant can be eaten, brewed in a tea or put into a tincture. It can also be vaporized using an e-cigarette pen. Yale University researchers surveyed 3,847 Connecticut high school students about this practice in a 2015 study that was published in the journal Pediatrics. The study found nearly one in five e-cigarette users also have vaporize cannabis or byproducts like hash oil using the device.
The world-leading producer of hemp is China, which produces more than 70% of the world output. France ranks second with about a quarter of the world production. Smaller production occurs in the rest of Europe, Chile, and North Korea. Over 30 countries produce industrial hemp, including Australia, Austria, Canada, Chile, China, Denmark, Egypt, Finland, Great Britain, Germany, Greece, Hungary, India, Italy, Japan, Korea, Netherlands, New Zealand, Poland, Portugal, Romania, Russia, Slovenia, Spain, Sweden, Switzerland, Thailand, Turkey and Ukraine.
Individuals who are considering participation in the Industrial Hemp Research Program in Kansas in 2019, whether as a grower, distributor or processor, can now submit a Pre-Application and Pre-Application Research Proposal. This is voluntary, and is not an application for a license, but will provide an opportunity to receive an informal review of your research proposal which can help expedite the process when the full research application is available.
Plastic composites for automobiles are the second most important component of the hemp industry of the EU. Natural fibers in automobile composites are used primarily in press-molded parts (Fig. 18). There are two widespread technologies. In thermoplastic production, natural fibers are blended with polypropylene fibers and formed into a mat, which is pressed under heat into the desired form. In thermoset production the natural fibers are soaked with binders such as epoxy resin or polyurethane, placed in the desired form, and allowed to harden through polymerization. Hemp has also been used in other types of thermoplastic applications, including injection molding. The characteristics of hemp fibers have proven to be superior for production of molded composites. In European manufacturing of cars, natural fibers are used to reinforce door panels, passenger rear decks, trunk linings, and pillars. In 1999 over 20,000 t of natural fiber were used for these purposes in Europe, including about, 2,000 t of hemp. It has been estimated that 5–10 kg of natural fibers can be used in the molded portions of an average automobile (excluding upholstery). The demand for automobile applications of hemp is expected to increase considerably, depending on the development of new technologies (Karus et al. 2000).
Canada is specialized on oilseed production and processing, so that hemp oil and grain are much more suitable than fiber. Because of the extensive development of oilseeds in Canada, there is extensive capacity to produce high-quality cold-pressed hemp oil. Canada in the last 5 years has made great advances in the growing, harvesting, and processing of hempseed, and indeed has moved ahead of the EU in the development of raw materials and products for the natural foods, nutraceuticals, and cosmetics industries. In the EU, a yield of 1 t/ha is considered good. In Canada, extraordinary yields of 1.5 t/ha have been realized, at least locally, although in the initial years of hempseed development in Canada yields were often less than 500 kg/ha. In 1999, the year of largest Canadian hemp acreage, yields averaged 900 kg/ha. (Ideally, hemp seed yield should be based on air dry weight—with about 12% moisture. Hemp yields are sometime uncertain, and could be exaggerated by as much as 50% when moist weights are reported.)
I don’t know a whole lot about the plants but a friend of mine who did weed told me hamper is just the stem of the cannabis. He would know, I wouldn’t. Sadly though he died June 10 of 2018 of stage 4 lung cancer. He was a heavy smoker and I just couldn’t be around it despite our best efforts to set up a ventilation system to fan the smoke out. I must be allergic to secondhand smoke though because I keep getting bronchitis every time I’m exposed to it for long enough and it doesn’t really take a real long time even under the best conditions. Second hand weed smoke really didn’t help either, with me smoke a smoke and I just can’t be around it as it becomes a serious issue. I’m still struggling with trying to get the junk out of my respiratory system that keeps building up in the very upper part of it
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner. In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity. A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.
Smoking cannabis can have an immediate effect. It can take an hour or more to feel the effects when eaten. Cannabis can make you feel relaxed, giggly, and hungry, or hallucinate or have a dry mouth. Using more cannabis can result in negative effects including blurred vision, bloodshot eyes, feeling sluggish, difficulty concentrating, slower reflexes, increased heart rate and lower blood pressure, and feelings of paranoia and anxiety.
The United Kingdom and Germany resumed commercial production in the 1990s. British production is mostly used as bedding for horses; other uses are under development. Companies in Canada, the UK, the United States, and Germany, among many others, process hemp seed into a growing range of food products and cosmetics; many traditional growing countries still continue to produce textile-grade fibre.