While cultivating marijuana’s non-intoxicating cousin is currently illegal in the U.S. outside of exceptions for state-approved hemp research programs authorized under the 2014 Farm Bill, there’s a strong possibility that industrial hemp will be broadly legalized—possibly by the end of the year—once the House and Senate reconcile their versions of a new Farm Bill and put it on the president’s desk.
Highly selected forms of the fiber cultigen possess features maximizing fiber production. Since the nodes tend to disrupt the length of the fiber bundles, thereby limiting quality, tall, relatively unbranched plants with long internodes have been selected. Another strategy has been to select stems that are hollow at the internodes, with limited wood, since this maximizes production of fiber in relation to supporting woody tissues. Similarly, limited seed productivity concentrates the plant’s energy into production of fiber, and fiber cultivars often have low genetic propensity for seed output. Selecting monoecious strains overcomes the problem of differential maturation times and quality of male (staminate) and female (pistillate) plants (males mature 1–3 weeks earlier). Male plants in general are taller, albeit slimmer, less robust, and less productive. Except for the troublesome characteristic of dying after anthesis, male traits are favored for fiber production, in contrast to the situation for drug strains noted below. In former, labor-intensive times, the male plants were harvested earlier than the females, to produce superior fiber. The limited branching of fiber cultivars is often compensated for by possession of large leaves with wide leaflets, which obviously increase the photosynthetic ability of the plants. Since fiber plants have not generally been selected for narcotic purposes, the level of intoxicating constituents is usually limited.
Pain management improves a patient’s quality of life throughout all stages of cancer. Through the study of cannabinoid receptors, endocannabinoids, and synthetic agonists and antagonists, the mechanisms of cannabinoid-induced analgesia have been analyzed.[Level of evidence:1iC] The CB1 receptor is found in the central nervous system (CNS) and in peripheral nerve terminals. CB2 receptors are located mainly in peripheral tissue and are expressed in only low amounts in the CNS. Whereas only CB1 agonists exert analgesic activity in the CNS, both CB1 and CB2 agonists have analgesic activity in peripheral tissue.[48,49]
Best Hemp CBD Products
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of Cannabis and cannabinoids in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
Selection for fiber has resulted in strains that have much more bark fiber tissues and much less woody core than encountered in narcotic strains, oilseed strains, and wild plants (Fig. 12). In non-fiber strains of Cannabis, bark can be less than one quarter of the stem tissues (i.e. more than three quarters can be woody core). By contrast, in fiber strains half of the stem tissues can be bark, and more than half of this can be the desirable long primary fibers (de Meijer 1995). Non-fiber strains rarely have as much as 15% fiber in the bark.
It is often claimed by growers and breeders of herbal cannabis that advances in breeding and cultivation techniques have increased the potency of cannabis since the late 1960s and early '70s when THC was first discovered and understood. However, potent seedless cannabis such as "Thai sticks" were already available at that time. Sinsemilla (Spanish for "without seed") is the dried, seedless inflorescences of female cannabis plants. Because THC production drops off once pollination occurs, the male plants (which produce little THC themselves) are eliminated before they shed pollen to prevent pollination. Advanced cultivation techniques such as hydroponics, cloning, high-intensity artificial lighting, and the sea of green method are frequently employed as a response (in part) to prohibition enforcement efforts that make outdoor cultivation more risky. It is often cited that the average levels of THC in cannabis sold in the United States rose dramatically between the 1970s and 2000, but such statements are likely skewed because undue weight is given to much more expensive and potent, but less prevalent samples.
The effects of delta-9-THC and a synthetic agonist of the CB2 receptor were investigated in HCC. Both agents reduced the viability of HCC cells in vitro and demonstrated antitumor effects in HCC subcutaneous xenografts in nude mice. The investigations documented that the anti-HCC effects are mediated by way of the CB2 receptor. Similar to findings in glioma cells, the cannabinoids were shown to trigger cell death through stimulation of an endoplasmic reticulum stress pathway that activates autophagy and promotes apoptosis. Other investigations have confirmed that CB1 and CB2 receptors may be potential targets in non-small cell lung carcinoma  and breast cancer.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.
Without arguing the merits of the above contentions, we point out that the legitimate use of hemp for non-intoxicant purposes has been inhibited by the continuing ferocious war against drug abuse. In this atmosphere, objective analysis has often been lacking. Unfortunately both proponents and opponents have tended to engage in exaggeration. Increasingly, however, the world is testing the potential of hemp in the field and marketplace, which surely must be the ultimate arbiters. De Guzman (2001), noting the pessimistic USDA report, observed that “Nevertheless, others point to the potential of [the] market. Hemp products have a growing niche market of their own, and the market will remain healthy and be well supported with many competing brands.”
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
Some jurisdictions use free voluntary treatment programs and/or mandatory treatment programs for frequent known users. Simple possession can carry long prison terms in some countries, particularly in East Asia, where the sale of cannabis may lead to a sentence of life in prison or even execution. Political parties, non-profit organizations, and causes based on the legalization of medical cannabis and/or legalizing the plant entirely (with some restrictions) have emerged in such countries as China and Thailand.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
μ-Opioid receptor agonists (opioids) (e.g., morphine, heroin, hydrocodone, oxycodone, opium, kratom) α2δ subunit-containing voltage-dependent calcium channels blockers (gabapentinoids) (e.g., gabapentin, pregabalin, phenibut) AMPA receptor antagonists (e.g., perampanel) CB1 receptor agonists (cannabinoids) (e.g., THC, cannabis) Dopamine receptor agonists (e.g., levodopa) Dopamine releasing agents (e.g., amphetamine, methamphetamine, MDMA, mephedrone) Dopamine reuptake inhibitors (e.g., cocaine, methylphenidate) GABAA receptor positive allosteric modulators (e.g., barbiturates, benzodiazepines, carbamates, ethanol (alcohol) (alcoholic drink), inhalants, nonbenzodiazepines, quinazolinones) GHB (sodium oxybate) and analogues Glucocorticoids (corticosteroids) (e.g., dexamethasone, prednisone) nACh receptor agonists (e.g., nicotine, tobacco, arecoline, areca nut) Nitric oxide prodrugs (e.g., alkyl nitrites (poppers)) NMDA receptor antagonists (e.g., DXM, ketamine, methoxetamine, nitrous oxide, phencyclidine, inhalants) Orexin receptor antagonists (e.g., suvorexant)
Neuropathic pain is a symptom cancer patients may experience, especially if treated with platinum-based chemotherapy or taxanes. Two RCTs of inhaled Cannabis in patients with peripheral neuropathy or neuropathic pain of various etiologies found that pain was reduced in patients who received inhaled Cannabis, compared with those who received placebo.[58,59] Two additional trials of inhaled Cannabis have also demonstrated the benefit of Cannabis over placebo in HIV-associated neuropathic pain.[60,61]
Hemp hasn't always been on the wrong side of the authorities. The Puritans brought hemp with them to New England in 1645 and Europeans were growing it even earlier in Chile. George Washington planted hemp as one of several crops at his Mount Vernon estate. However, hemp's popularity waned in America as other plants used for textiles such as cotton and jute became more widely available. The U.S. Navy briefly campaigned for more hemp farming during World War II to supply ropes for ships. But the federal government continued restrictions on hemp after the war.
In addition to providing useful fibers, hemp seed also has high nutritional value. and the plant can be used to make biodegradable plastics, some fuels, and a variety of other things. Hemp foods including but not limited to hemp energy bars, hemp salad dressing,hemp milk, hemp protein shakes, hemp oil gel caps and hemp protein powder are among some of the health products being produced today. Visit the Hemp Education pages to learn more!
The Montana Department of Agriculture is not responsible for a pilot participant’s business plan or activities and will not be a mediator between pilot participants and any business associates or partners. We encourage interested individuals to contact a hemp trade association to learn more about marketing opportunities, such as the Hemp Industries Association or the National Hemp Association.
The most widespread claim for environmental friendliness of hemp is that it has the potential to save trees that otherwise would be harvested for production of lumber and pulp. Earlier, the limitations of hemp as a pulp substitute were examined. With respect to wood products, several factors appear to favor increased use of wood substitutes, especially agricultural fibers such as hemp. Deforestation, particularly the destruction of old growth forests, and the world’s decreasing supply of wild timber resources are today major ecological concerns. Agroforestry using tree species is one useful response, but nevertheless sacrifices wild lands and biodiversity, and is less preferable than sustainable wildland forestry. The use of agricultural residues (e.g. straw bales in house construction) is an especially environmentally friendly solution to sparing trees, but material limitations restrict use. Another chief advantage of several annual fiber crops over forestry crops is relative productivity, annual fiber crops sometimes producing of the order of four times as much per unit of land. Still another important advantage is the precise control over production quantities and schedule that is possible with annual crops. In many parts of the world, tree crops are simply not a viable alternative. “By the turn of the century 3 billion people may live in areas where wood is cut faster than it grows or where fuelwood is extremely scarce” (World Commission on Environment and Development 1987). “Since mid-century, lumber use has tripled, paper use has increased six-fold, and firewood use has soared as Third World populations have multiplied” (Brown et al. 1998). Insofar as hemp reduces the need to harvest trees for building materials or other products, its use as a wood substitute will tend to contribute to preserving biodiversity. Hemp may also enhance forestry management by responding to short-term fiber demand while trees reach their ideal maturation. In developing countries where fuelwood is becoming increasingly scarce and food security is a concern, the introduction of a dual-purpose crop such as hemp to meet food, shelter, and fuel needs may contribute significantly to preserving biodiversity.
As I research more I am disgusted with how we have all been deceived. I feel confident now with being able to research things on our own, at any moment in time, we can begin to take back our world. In the early 30’s one of the great media conspiracies unfolded. Publisher William Hearst, Dupont, the petroleum interests, the cotton lobby, the bankers and some ignorant politicians lead a crusade to ban hemp to line their pockets. Hemp can revolutionize our society. Please research and pass on!
This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.
One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors. During this 2-year study, groups of mice and rats were given various doses of THC by gavage. A dose-related decrease in the incidence of hepatic adenoma tumors and hepatocellular carcinoma (HCC) was observed in the mice. Decreased incidences of benign tumors (polyps and adenomas) in other organs (mammary gland, uterus, pituitary, testis, and pancreas) were also noted in the rats. In another study, delta-9-THC, delta-8-THC, and cannabinol were found to inhibit the growth of Lewis lung adenocarcinoma cells in vitro and in vivo . In addition, other tumors have been shown to be sensitive to cannabinoid-induced growth inhibition.[5-8]
Fig. 11. Frequency histograms of THC concentration in germplasm collections. Left, collection of E. Small and D. Marcus; of the 167 accessions, 43% had THC levels >0.3%. Right, the collection of the Vavilov Institute, St. Petersburg; of the 278 accessions for which chemical analyses were reported in Anonymous (1975), about 55% had THC levels >0.3%.
As the range of Tweed and CraftGrow brands and products will change in the Shop over time, we recommend the Spectrum Cannabis brand when consistent access to the same product is important to you and your condition. If you have been taking a Tweed product that is no longer carried or available in our store, we have created a comprehensive table for you to explore alternative options. The goal of this table is to support treatment decisions with products most similar to what you have been taking, when a change is necessary. Learn More