Some users may experience an episode of acute psychosis, which usually abates after six hours, but in rare instances, heavy users may find the symptoms continuing for many days.[52] A reduced quality of life is associated with heavy cannabis use, although the relationship is inconsistent and weaker than for tobacco and other substances.[53] It is unclear, however, if the relationship is cause and effect.[53]

In 1937, the U.S. Treasury Department introduced the Marihuana Tax Act. This Act imposed a levy of $1 per ounce for medicinal use of Cannabis and $100 per ounce for nonmedical use. Physicians in the United States were the principal opponents of the Act. The American Medical Association (AMA) opposed the Act because physicians were required to pay a special tax for prescribing Cannabis, use special order forms to procure it, and keep special records concerning its professional use. In addition, the AMA believed that objective evidence that Cannabis was harmful was lacking and that passage of the Act would impede further research into its medicinal worth.[6] In 1942, Cannabis was removed from the U.S. Pharmacopoeia because of persistent concerns about its potential to cause harm.[2,3]

I suffer fr migraines. Currently having Botox injections every three months for the last three years. This has helped went fr 24 to 30 migraines a month to 6 to 8 , now I'm back up to 14 to 20 a month. My doctor thought CBD oil might help. I have also started having anxiety attacks for a year now. I'm really confused with the dosages. Any thoughts would b helpful
Preclinical research suggests that emetic circuitry is tonically controlled by endocannabinoids. The antiemetic action of cannabinoids is believed to be mediated via interaction with the 5-hydroxytryptamine 3 (5-HT3) receptor. CB1 receptors and 5-HT3 receptors are colocalized on gamma-aminobutyric acid (GABA)-ergic neurons, where they have opposite effects on GABA release.[35] There also may be direct inhibition of 5-HT3 gated ion currents through non–CB1 receptor pathways. CB1 receptor antagonists have been shown to elicit emesis in the least shrew that is reversed by cannabinoid agonists.[36] The involvement of CB1 receptor in emesis prevention has been shown by the ability of CB1 antagonists to reverse the effects of THC and other synthetic cannabinoid CB1 agonists in suppressing vomiting caused by cisplatin in the house musk shrew and lithium chloride in the least shrew. In the latter model, CBD was also shown to be efficacious.[37,38]
It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.
Nevertheless, every bit of this ancient plant is useful and valuable, and not just for rope, but for textiles, auto parts, cosmetics, dynamite, supplements, food, and medicine. In ancient China, hemp seed was regarded as food for the lower classes, and in Europe, a peanut butter-like spread was made from the seeds, in both cases with the hulls intact.
Ten trials have evaluated the efficacy of inhaled Cannabis in chemotherapy-induced N/V.[35-38] In two of the studies, inhaled Cannabis was made available only after dronabinol failure. In the first trial, no antiemetic effect was achieved with marijuana in patients receiving cyclophosphamide or doxorubicin,[35] but in the second trial, a statistically significant superior antiemetic effect of inhaled Cannabis versus placebo was found among patients receiving high-dose methotrexate.[36] The third trial was a randomized, double-blind, placebo-controlled, crossover trial involving 20 adults in which both inhaled marijuana and oral THC were evaluated. One-quarter of the patients reported a favorable antiemetic response to the cannabinoid therapies. This latter study was reported in abstract form in 1984. A full report, detailing the methods and outcomes apparently has not been published, which limits a thorough interpretation of the significance of these findings.[37]

In recent decades, the neurobiology of cannabinoids has been analyzed.[12-15] The first cannabinoid receptor, CB1, was identified in the brain in 1988. A second cannabinoid receptor, CB2, was identified in 1993. The highest expression of CB2 receptors is located on B lymphocytes and natural killer cells, suggesting a possible role in immunity. Endogenous cannabinoids (endocannabinoids) have been identified and appear to have a role in pain modulation, control of movement, feeding behavior, mood, bone growth, inflammation, neuroprotection, and memory.[16]
Spring Hope, NC, Nov. 16, 2018 (GLOBE NEWSWIRE) -- via NEWMEDIAWIRE -- Hemp, Inc. (OTC PINK: HEMP), a global leader in the industrial hemp industry with bi-coastal processing centers including the largest multipurpose industrial hemp processing facility in the western hemisphere (in Spring Hope, North Carolina), announced today Senate Majority Leader Mitch McConnell (R-Ky.) has confirmed the provision legalizing hemp as an agricultural commodity will be included in the final version of the 2018 Farm Bill. McConnell initially introduced the Hemp Farming Act of 2018 in the Senate’s version of the farm bill including provisions to legalize hemp, remove it from the federal list of controlled substances and allow it to be sold as an agricultural commodity. When passed, the bill would also allow states to regulate hemp, as well as allow hemp researchers to apply for grants from the Agriculture Department and make hemp farmers eligible for crop insurance.

Hemp, (Cannabis sativa), also called industrial hemp, plant of the family Cannabaceae cultivated for its fibre (bast fibre) or its edible seeds. Hemp is sometimes confused with the cannabis plants that serve as sources of the drug marijuana and the drug preparation hashish. Although all three products—hemp, marijuana, and hashish—contain tetrahydrocannabinol (THC), a compound that produces psychoactive effects in humans, the variety of cannabis cultivated for hemp has only small amounts of THC relative to that grown for the production of marijuana or hashish.
A 100-gram portion of hulled hemp seeds supplies 586 calories. They contain 5% water, 5% carbohydrates, 49% total fat, and 31% protein. Hemp seeds are notable in providing 64% of the Daily Value (DV) of protein per 100-gram serving.[19] Hemp seeds are a rich source of dietary fiber (20% DV), B vitamins, and the dietary minerals manganese (362% DV), phosphorus (236% DV), magnesium (197% DV), zinc (104% DV), and iron (61% DV). About 73% of the energy in hempseed is in the form of fats and essential fatty acids,[19] mainly polyunsaturated fatty acids, linoleic, oleic, and alpha-linolenic acids.[20]
One of the reasons hemp fiber has been valued is because of its length. The primary bast fibers in the bark are 5–40 mm long, and are amalgamated in fiber bundles which can be 1–5 m long (secondary bast fibers are about 2 mm long). The woody core fibers are short—about 0.55 mm—and like hardwood fibers are cemented together with considerable lignin. The core fibers are generally considered too short for high grade paper applications (a length of 3 mm is considered ideal), and too much lignin is present. While the long bast fibers have been used to make paper almost for 2 millennia, the woody core fibers have rarely been so used. Nevertheless it has been suggested that the core fibers could be used for paper making, providing appropriate technology was developed (de Groot et al. 1998). In any event, the core fibers, have found a variety of uses, as detailed below. The long, lignin-poor bast fibers also have considerable potential to be used in many non-paper, non-textile applications, as noted below.
CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
Representations regarding the efficacy and safety of CBDPure have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
CBC is another lesser-known yet still crucial cannabinoid in marijuana, especially from a therapeutic perspective. While bereft of the psychoactive quality of THC (and to a lesser extent THCV), CBC is gaining popularity as an anxiety reducer. While research on cannabichromene lags behind others, there’s good reason to continue looking into its potential as a medicine.
Given its name, you might assume THCV shares psychoactive powers with its potent counterpart, THC. In reality, this cannabinoid is more like a cross between CBD and THC. From the former, it takes its modulating powers. Acting like THC “lite,” THCV like CBD can dampen the effects of a strong high. Yet at higher doses, THCV kicks into a psychoactive stimulant in its own right.
The basic commercial options for growing hemp in North America is as a fiber plant, an oilseed crop, or for dual harvest for both seeds and fiber. Judged on experience in Canada to date, the industry is inclined to specialize on either fiber or grain, but not both. Hemp in our opinion is particularly suited to be developed as an oilseed crop in North America. The first and foremost breeding goal is to decrease the price of hempseed by creating more productive cultivars. While the breeding of hemp fiber cultivars has proceeded to the point that only slight improvements can be expected in productivity in the future, the genetic potential of hemp as an oilseed has scarcely been addressed. From the point of view of world markets, concentrating on oilseed hemp makes sense, because Europe has shown only limited interest to date in developing oilseed hemp, whereas a tradition of concentrating on profitable oilseed products is already well established in the US and Canada. Further, China’s supremacy in the production of high-quality hemp textiles at low prices will be very difficult to match, while domestic production of oilseeds can be carried out using technology that is already available. The present productivity of oilseed hemp—about 1 t/ha under good conditions, and occasional reports of 1.5 to 2 t/ha, is not yet sufficient for the crop to become competitive with North America’s major oilseeds. We suggest that an average productivity of 2 t/ha will be necessary to transform hempseed into a major oilseed, and that this breeding goal is achievable. At present, losses of 30% of the seed yields are not uncommon, so that improvements in harvesting technology should also contribute to higher yields. Hemp food products cannot escape their niche market status until the price of hempseed rivals that of other oilseeds, particularly rapeseed, flax, and sunflower. Most hemp breeding that has been conducted to date has been for fiber characteristics, so that there should be considerable improvement possible. The second breeding goal is for larger seeds, as these are more easily shelled. Third is breeding for specific seed components. Notable are the health-promoting gamma-linolenic acid; improving the amino acid spectrum of the protein; and increasing the antioxidant level, which would not only have health benefits but could increase the shelf life of hemp oil and foods.
Probably indigenous to temperate Asia, C. sativa is the most widely cited example of a “camp follower.” It was pre-adapted to thrive in the manured soils around man’s early settlements, which quickly led to its domestication (Schultes 1970). Hemp was harvested by the Chinese 8500 years ago (Schultes and Hofmann 1980). For most of its history, C. sativa was most valued as a fiber source, considerably less so as an intoxicant, and only to a limited extent as an oilseed crop. Hemp is one of the oldest sources of textile fiber, with extant remains of hempen cloth trailing back 6 millennia. Hemp grown for fiber was introduced to western Asia and Egypt, and subsequently to Europe somewhere between 1000 and 2000 BCE. Cultivation in Europe became widespread after 500 ce. The crop was first brought to South America in 1545, in Chile, and to North America in Port Royal, Acadia in 1606. The hemp industry flourished in Kentucky, Missouri, and Illinois between 1840 and 1860 because of the strong demand for sailcloth and cordage (Ehrensing 1998). From the end of the Civil War until 1912, virtually all hemp in the US was produced in Kentucky. During World War I, some hemp cultivation occurred in several states, including Kentucky, Wisconsin, California, North Dakota, South Dakota, Minnesota, Indiana, Illinois, Ohio, Michigan, Kansas, and Iowa (Ehrensing 1998). The second world war led to a brief revival of hemp cultivation in the Midwest, as well as in Canada, because the war cut off supplies of fiber (substantial renewed cultivation also occurred in Germany for the same reason). Until the beginning of the 19th century, hemp was the leading cordage fiber. Until the middle of the 19th century, hemp rivaled flax as the chief textile fiber of vegetable origin, and indeed was described as “the king of fiber-bearing plants,—the standard by which all other fibers are measured” (Boyce 1900). Nevertheless, the Marihuana Tax Act applied in 1938 essentially ended hemp production in the United States, although a small hemp fiber industry continued in Wisconsin until 1958. Similarly in 1938 the cultivation of Cannabis became illegal in Canada under the Opium and Narcotics Act.

“Folks at the various state Departments of Agriculture are so excited to bring in hemp – excited to introduce any crop, really, and especially to reintroduce this extraordinarily versatile one,” Beckerman said. “But they’re not experts; they’re learning like anybody else. So getting in there, looking at proposed legislation and rules to make sure [proposals] actually make sense for the crop – on an agronomic level, on a regulatory level – and monitoring changes to that legislation, regulation, or industry, is common sense.” She went on,
The confusion between industrial hemp and marijuana is based on the visual similarities of widely differentiated varieties of plants. By definition, industrial hemp is high in fiber and low in active tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana that makes some cannabis varieties a valued drug. Canada and the European Union maintain this distinction by strictly regulating the THC levels of industrial hemp, requiring it to be less than 0.3 percent, compared to THC levels of between 3 to 30 percent in marijuana.
The first example of the use of hempcrete was in 1986 in France with the renovation of the Maison de la Turquie in Nogent-sur-Seine by the innovator Charles Rasetti.[27] In the UK hemp lime was first used in 2000 for the construction of two test dwellings in Haverhill.[28] Designed by Modece Architects,[29] who pioneered hemp's use in UK construction, the hemp houses were monitored in comparison with other standard dwellings by BRE. Completed in 2009, the Renewable House is one of the most technologically advanced made from hemp-based materials.[30] The first US home made of hemp-based materials was completed in August 2010 in Asheville, North Carolina.[31]