As noted above, hemp seed cake makes an excellent feed for animals. However, feeding entire plants is another matter, because the leaves are covered with the resin-producing glands. While deer, groundhogs, rabbits, and other mammals will nibble on hemp plants, mammals generally do not choose to eat hemp. Jain and Arora (1988) fed narcotic Cannabis refuse to cattle, and found that the animals “suffered variable degrees of depression and revealed incoordination in movement.” By contrast, Letniak et al. (2000) conducted an experimental trial of hemp as silage. No significant differences were found between yield of the hemp and of barley/oat silage fed to heifers, suggesting that fermenting hemp plants reduces possible harmful constituents.
Cannabis use generally makes psychotic symptoms worse and lowers the person’s chances of recovery from a psychotic episode. People with a psychotic illness who use drugs experience more delusions, hallucinations and other symptoms. They have a higher rate of hospitalisation for psychosis, and treatment is generally less effective for them. People with a psychotic illness should not use cannabis.
Retting is generally done in the field (Fig. 46, 47). This typically requires weeks. The windrows should be turned once or twice. If not turned, the stems close to the ground will remain green while the top ones are retted and turn brown. When the stalks have become sufficiently retted requires experience—the fibers should have turned golden or grayish in color, and should separate easily from the interior wood. Baling can be done with any kind of baler (Fig. 48). Stalks should have less than 15% moisture when baled, and should be allowed to dry to about 10% in storage. Bales must be stored indoors. Retted stalks are loosely held together, and for highest quality fiber applications need to be decorticated, scutched, hackled, and combed to remove the remaining pieces of stalks, broken fibers, and extraneous material. The equipment for this is rare in North America, and consequently use of domestically-produced fiber for high quality textile applications is extremely limited. However, as described above relatively crude fiber preparations also have applications.
In modern times, the Rastafari movement has embraced Cannabis as a sacrament. Elders of the Ethiopian Zion Coptic Church, a religious movement founded in the United States in 1975 with no ties to either Ethiopia or the Coptic Church, consider Cannabis to be the Eucharist, claiming it as an oral tradition from Ethiopia dating back to the time of Christ. Like the Rastafari, some modern Gnostic Christian sects have asserted that Cannabis is the Tree of Life. Other organized religions founded in the 20th century that treat Cannabis as a sacrament are the THC Ministry, Cantheism, the Cannabis Assembly and the Church of Cognizance. Rastafarians tend to be among the biggest consumers of modern Cannabis use.
The Drug Enforcement Agency and the Office of National Drug Control Policy of the US raised concerns over tests conducted from 1995 to 1997 that showed that consumption of hempseed products available during that period led to interference with drug-testing programs for marijuana use. Federal US programs utilize a THC metabolite level of 50 parts per billion in urine. Leson (2000) found that this level was not exceeded by consuming hemp products, provided that THC levels are maintained below 5 ppm in hemp oil, and below 2 ppm in hulled seeds. Nevertheless the presence of even minute trace amounts of THC in foods remains a tool that can be used by those wishing to prevent the hemp oilseed industry from developing.
Also high in fiber, hemp seeds are more digestible than any other high-protein food, including meat, cheese, eggs, human milk, or cows’ milk. They’re high in antioxidants, and minerals like iron, zinc and copper as well as calcium, magnesium, potassium, carotene, thiamin (vitamin B1), riboflavin (vitamin B2), vitamin B6 and vitamin E. If that’s not enough, there’s also chlorophyll, sulfur, phosphorus, phospholipids, and phytosterols.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain. It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12. Although currently classified as orphan receptors, these receptors are most closely related phylogeneticaly to the cannabinoid receptors. In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist, and this action may be involved in its antidepressant, anxiolytic, and neuroprotective effects. It is an allosteric modulator of the μ- and δ-opioid receptors as well. The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.
Cannabis research suggests medical marijuana could become an effective treatment for diabetic neuropathy. Diabetic neuropathy is a debilitating and sometimes fatal condition caused by diabetes. Diabetics suffer from high blood sugar due to insulin resistance, and this damages nerve cells in the body, causing severe pain. Patients who consumed THC as part of a study found they experienced less pain. Findings are not definitive, however, and further research into cannabis as a treatment for diabetes and associated symptoms is required.
^ Jump up to: a b Weinstein A, Livny A, Weizman A (2016). "Brain Imaging Studies on the Cognitive, Pharmacological and Neurobiological Effects of Cannabis in Humans: Evidence from Studies of Adult Users". Current Pharmaceutical Design. 22 (42): 6366–6379. doi:10.2174/1381612822666160822151323. PMID 27549374. 1)The studies reviewed so far demonstrated that chronic cannabis use has been associated with a volume reduction of the hippocampus...3)The overall conclusion arising from these studies is that recent cannabis users may experience subtle neurophysiological deficits while performing on working memory tasks, and that they compensate for these deficits by "working harder" by using additional brain regions to meet the demands of the task.
An alternative to the gateway hypothesis is the common liability to addiction (CLA) theory. It states that some individuals are, for various reasons, willing to try multiple recreational substances. The "gateway" drugs are merely those that are (usually) available at an earlier age than the harder drugs. Researchers have noted in an extensive review that it is dangerous to present the sequence of events described in gateway "theory" in causative terms as this hinders both research and intervention.
CBD does not appear to have any psychotropic ("high") effects such as those caused by ∆9-THC in marijuana, but may have anti-anxiety and anti-psychotic effects. As the legal landscape and understanding about the differences in medical cannabinoids unfolds, it will be increasingly important to distinguish "medical marijuana" (with varying degrees of psychotropic effects and deficits in executive function) – from "medical CBD therapies” which would commonly present as having a reduced or non-psychoactive side effect profile.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
The basic commercial options for growing hemp in North America is as a fiber plant, an oilseed crop, or for dual harvest for both seeds and fiber. Judged on experience in Canada to date, the industry is inclined to specialize on either fiber or grain, but not both. Hemp in our opinion is particularly suited to be developed as an oilseed crop in North America. The first and foremost breeding goal is to decrease the price of hempseed by creating more productive cultivars. While the breeding of hemp fiber cultivars has proceeded to the point that only slight improvements can be expected in productivity in the future, the genetic potential of hemp as an oilseed has scarcely been addressed. From the point of view of world markets, concentrating on oilseed hemp makes sense, because Europe has shown only limited interest to date in developing oilseed hemp, whereas a tradition of concentrating on profitable oilseed products is already well established in the US and Canada. Further, China’s supremacy in the production of high-quality hemp textiles at low prices will be very difficult to match, while domestic production of oilseeds can be carried out using technology that is already available. The present productivity of oilseed hemp—about 1 t/ha under good conditions, and occasional reports of 1.5 to 2 t/ha, is not yet sufficient for the crop to become competitive with North America’s major oilseeds. We suggest that an average productivity of 2 t/ha will be necessary to transform hempseed into a major oilseed, and that this breeding goal is achievable. At present, losses of 30% of the seed yields are not uncommon, so that improvements in harvesting technology should also contribute to higher yields. Hemp food products cannot escape their niche market status until the price of hempseed rivals that of other oilseeds, particularly rapeseed, flax, and sunflower. Most hemp breeding that has been conducted to date has been for fiber characteristics, so that there should be considerable improvement possible. The second breeding goal is for larger seeds, as these are more easily shelled. Third is breeding for specific seed components. Notable are the health-promoting gamma-linolenic acid; improving the amino acid spectrum of the protein; and increasing the antioxidant level, which would not only have health benefits but could increase the shelf life of hemp oil and foods.
In the Australian states of Tasmania, Victoria, Queensland, and most recently, New South Wales, the state governments have issued licences to grow hemp for industrial use. The first to initiate modern research into the potential of cannabis was the state of Tasmania, which pioneered the licensing of hemp during the early 1990s. The state of Victoria was an early adopter in 1998, and has reissued the regulation in 2008.
But all was not well. Harper has continued to experience health issues related to her condition. And seven months after starting to use CBD oil, Harper’s seizures returned— although not as frequently as before. Penny uses eleven iPhone reminders to keep track of Harper’s daily regimen of medications and food, and she records all of Harper’s seizures in a thickly bound black book. But as her parents continue to closely monitor Harper’s health and adjust her medications accordingly, her doctors are tightly limited in the advice they can offer when it comes to CBD oil. “There’s no research on this product, so they don’t say it’s good or bad. They just say, ‘Don’t stop giving it,’” Penny told me.
In early June, I met with Penny Pennington Howard, a mother of three, who lives in Carrollton, Texas, about 25 minutes outside of Dallas. Posted in the glass of her front door are two signs you can’t quite make out from the sidewalk: one asking visitors not to smoke, as oxygen treatments are in use; the other a yellow diamond informing guests this is the home of a special needs child. Penny welcomed me inside, out of the glare of the sun, and led me through her living room into her kitchen, where her kids were gathered for lunch. Seth, then eight months old, was plucking cereal off the tray of his highchair, while Lily, seven, was darting back and forth between the countertop and table. Harper, a blond five-year-old with hot pink toenails, was reclining in her “tomato chair,” a molded plastic seat with straps to help keep her steady.
States have passed laws creating or allowing for the establishment of industrial hemp research or pilot programs. State agencies and institutions of higher education administer these programs in order to study the cultivation, processing, and economics of industrial hemp. Pilot programs may be limited to a certain period of time and may require periodic reporting from participants and state agencies. Some states establish specific regulatory agencies or committees, rules, and goals to oversee the research programs. States may also require coordination between specific colleges or universities and the programs, in other states coordination is optional. From 2015 to 2016, seven states enacted legislation to create hemp research or pilot programs, including Pennsylvania (H.B. 976) and Hawaii (S.B. 2659).
Because C. sativa has been a neglected crop for so long in North America, there are only negligible genetic resources available on this continent. Most germplasm stocks of hemp are in Europe, and the largest and most important collection is the Vavilov Institute gene bank in Leningrad. Figure 11 shows THC concentrations in the Vavilov collection, as well as in our own collection, largely of European germplasm. A disturbingly high percentage of the collections have THC levels higher than 0.3%, making it difficult to incorporate these into breeding programs.
It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
In 2014, I founded New Frontier Data, an analytics and business intelligence reporting group dedicated to the global cannabis industry, after more than 20 years in finance, industry analytics, intelligence reporting and emerging markets. As such, I have had the privilege of following hemp’s emergence and evolution. Half a decade later, this robust, environmentally friendly, low -cost-to-produce plant has become one of the most diversely applied and globally significant natural resources in the world. Here is a look at its applications across several mature industries:
In 1937, the U.S. Treasury Department introduced the Marihuana Tax Act. This Act imposed a levy of $1 per ounce for medicinal use of Cannabis and $100 per ounce for nonmedical use. Physicians in the United States were the principal opponents of the Act. The American Medical Association (AMA) opposed the Act because physicians were required to pay a special tax for prescribing Cannabis, use special order forms to procure it, and keep special records concerning its professional use. In addition, the AMA believed that objective evidence that Cannabis was harmful was lacking and that passage of the Act would impede further research into its medicinal worth. In 1942, Cannabis was removed from the U.S. Pharmacopoeia because of persistent concerns about its potential to cause harm.[2,3]
The Duquenois–Levine test is commonly used as a screening test in the field, but it cannot definitively confirm the presence of cannabis, as a large range of substances have been shown to give false positives. Despite this, it is common in the United States for prosecutors to seek plea bargains on the basis of positive D–L tests, claiming them to be conclusive, or even to seek conviction without the use of gas chromatography confirmation, which can only be done in the lab. In 2011, researchers at John Jay College of Criminal Justice reported that dietary zinc supplements can mask the presence of THC and other drugs in urine. However, a 2013 study conducted by researchers at the University of Utah School of Medicine refute the possibility of self-administered zinc producing false-negative urine drug tests.
Figuring out how much CBD oil to take can feel like trying to navigate through a complicated maze. The sheer volume of CBD brands on the market can create confusion for consumers, and when you take a closer look, it’s not difficult to understand why. Not only do vendors use different source materials (CBD-rich cannabis vs. industrial hemp, different strains, etc.), but they also implement different extraction techniques .
In the United States, the legality of medical marijuana varies in substantial ways from state to state. There are currently 29 US states with legal medical cannabis laws, as well as the District of Columbia. That leaves 21 states where medical marijuana is entirely prohibited. Marijuana cultivation, possession, and use in any form is illegal at the federal level.
In 2013, BMW announced its newest electric car, the i3. Using low-weight hemp in its interior, the i3 weighs 800 pounds less than its market competitors. The Kestrel, created by Canadian Motive Industries, uses polymer resin-infused hemp stalks to replace fiberglass in the body of the vehicle. From this replacement, consumers can expect a dramatic reduction in weight, improved efficiency and the appeal of an ecologically sustainable vehicle.
These CBD-only laws also attempt to impose some regulation on CBD oils, such as establishing how much CBD and THC such products must contain. For example, on June 1, the day I sat down with Hernandez in Fort Worth, Texas, Governor Greg Abbott signed the state’s Compassionate Use Act into law in Austin. The law requires that all CBD products contain no more than 0.5 percent THC and at least 10 percent CBD. However, the bill does not specify how the state plans to enforce this requirement. The law contains no language outlining how laboratories can test CBD products, what kinds of standards they would use, or who would regulate them.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.
Breeding for low THC cultivars in Europe has been reviewed by Bócsa (1998), Bócsa and Karus (1998), and Virovets (1996). Some researchers have claimed to have produced essentially THC-free strains, although at present no commercial cultivar seems to be 100% free of THC. THC content has proven to be more easily reduced in monoecious than in dioecious varieties. It should be possible to select THC-free strains, and there has been speculation that genetic engineering could be helpful in this regard. As a strategic economic and political tactic, France has been attempting for several years to have the European Union (EU) adopt legislation forbidding the cultivation of industrial hemp cultivars with more than 0.1% THC, which would mean that primarily French varieties would have to be cultivated in Europe. However, the Canadian government has found that some French material has proven to be excessively high in THC.
Hemp paper is useful for specialty applications such as currency and cigarette papers where strength is needed. The bast fiber is of greatest interest to the pulp and paper industry because of its superior strength properties compared to wood. However, the short, bulky fibers found in the inner part of the plant (hurds) can also be used to make cheaper grades of paper, apparently without greatly affecting quality of the printing surface. Hemp is not competitive for newsprint, books, writing papers, and general paper (grocery bags, coffee cups, napkins), although there is a specialty or novelty market for those specifically wishing to support the hemp industry by purchasing hemp writing or printing paper despite the premium price (Fig. 17).
Representations regarding the efficacy and safety of CBDPure have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
Jump up ^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.
If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.
Cannabis lowers the pressure in the eye that causes optic nerve damage leading to glaucoma. Research has shown conclusively that marijuana users experience lower internal eye pressure while the body metabolizes THC. However, the psychoactive side effects of using THC to treat glaucoma make cannabis a nonviable medication for most people with the disease.
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That being said, it was unlikely that the federal government was interested in pursuing individuals complying with state-mandated regulations surrounding legalized cannabis for recreational use, although the CSA law still gives them authority to do so. However, the new Trump administration may change this thinking and users of legal marijuana and legal dispensaries await further action and clarifying rules.
In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.
Hi, Congrats on finishing chemo & radiation that’s awesome!! I wish you the best of luck!! I was actually wanting to know about dosage for cancer as well..My parents both have recently been diagnosed with cancer 4 months apart and are currently going thru chemo together. I have tried looking for the dosage info but can never find what i’m looking for..I want to try to help lesson the chemo side effects and hopefully kill some of the cancer cells. Can someone please help us?Thank You Christy
One of the biggest players in this new industry is Medical Marijuana, Inc., a company formed in 2009 that operates out of Poway, California, just north of San Diego. It has played a leading role in the so-called Green Rush, as businesses have moved quickly to capitalize on the gradual legalization of marijuana for medical and recreational purposes by states across the country. The company’s spokesman, Andrew Hard, boasted that Medical Marijuana, Inc., “created the CBD industry and was first to market with CBD products.” Through its various subsidiaries, Medical Marijuana, Inc. sells some of the most recognizable products on the cannabis market— everything from Cibaderm CBD-infused shampoo to CanChew chewing gum. In 2014, the company generated $14.5 million in revenue.
Over the past two years, 17 states have passed laws legalizing CBD so that patients can obtain the drug without fear of prosecution from local authorities. For intractable childhood epilepsies—the sorts of seizure disorders that for centuries have ruined lives and shattered families, the ones even specialists like Hernandez dread—CBD could be a miracle cure.
Earliest reference to euphoric use of C. sativa appears to date to China of 5 millennia ago, but it was in India over the last millennium that drug consumption became more firmly entrenched than anywhere else in the world. Not surprisingly, the most highly domesticated drug strains were selected in India. While C. sativa has been used as a euphoriant in India, the Near East, parts of Africa, and other Old World areas for thousands of years, such use simply did not develop in temperate countries where hemp was raised. The use of C. sativa as a recreational inebriant in sophisticated, largely urban settings is substantially a 20th century phenomenon.
Users have reported toxic symptoms, extreme reactions and serious psychological problems from using synthetic cannabis. These include: high blood, pressure, abdominal pain, nausea and vomiting, chest pain, heart palpitations, severe anxiety and paranoia, fear of dying, hallucinations, tremors and seizures, violent behaviour, and suicidal thoughts. These toxic symptoms have lasting several days and others have experienced long term mental health issues. Tolerance can develop quickly which means you will need more to get the same effect.
Although marijuana smoke contains a number of carcinogens findings from a limited number of well-designed studies do not suggest an increased risk for the development of either lung or upper airway cancer from light or moderate use. However, the evidence is mixed when it comes to the carcinogenic risks of heavy, long-term marijuana users, according to this study.
Jump up ^ Crean RD, Crane NA, Mason BJ (March 2011). "An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions". Journal of Addiction Medicine. 5 (1): 1–8. doi:10.1097/ADM.0b013e31820c23fa. PMC 3037578. PMID 21321675. Cannabis appears to continue to exert impairing effects in executive functions even after 3 weeks of abstinence and beyond. While basic attentional and working memory abilities are largely restored, the most enduring and detectable deficits are seen in decision-making, concept formation and planning.
Pain management improves a patient’s quality of life throughout all stages of cancer. Through the study of cannabinoid receptors, endocannabinoids, and synthetic agonists and antagonists, the mechanisms of cannabinoid-induced analgesia have been analyzed.[Level of evidence:1iC] The CB1 receptor is found in the central nervous system (CNS) and in peripheral nerve terminals. CB2 receptors are located mainly in peripheral tissue and are expressed in only low amounts in the CNS. Whereas only CB1 agonists exert analgesic activity in the CNS, both CB1 and CB2 agonists have analgesic activity in peripheral tissue.[48,49]
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