CDFA's Commercial Feed Regulatory Program (CFRP) is responsible for the enforcement of California state law and regulations pertinent to the manufacturing, distribution and labeling of commercial livestock feed while preventing adulterated feed from being consumed by livestock and poultry. For more information regarding livestock feed, contact CDFA's CFRP.
"Right now, any claims and dosing recommendations by any company making a CBD product for the medical marijuana market is purely anecdotal," he says. "Asking 100 people who use your product whether they feel better isn't real science. The products on the market are also different from what was used in the scientific studies that they are basing their claims upon. If a study found an anti-anxiety effect when dosing humans with synthetic CBD, that doesn't mean that your CBD oil that contains 18 percent CBD is going to reduce anxiety. It might even have the opposite effect."
The above uses are based on hemp as a mechanical strengthener of materials. Hemp can also be chemically combined with materials. For example, hemp with gypsum and binding agents may produce light panels that might compete with drywall. Hemp and lime mixtures make a high quality plaster. Hemp hurds are rich in silica (which occurs naturally in sand and flint), and the hurds mixed with lime undergo mineralization, to produce a stone-like material. The technology is most advanced in France (Fig. 26). The mineralized material can be blown or poured into the cavities of walls and in attics as insulation. The foundations, walls, floors, and ceilings of houses have been made using hemp hurds mixed with natural lime and water. Sometimes plaster of Paris (pure gypsum), cement, or sand is added. The resulting material can be poured like concrete, but has a texture vaguely reminiscent of cork—much lighter than cement, and with better heat and sound-insulating properties. An experimental “ceramic tile” made of hemp has recently been produced (Fig. 27).
About 9% of those who experiment with marijuana eventually become dependent according to DSM-IV (1994) criteria. A 2013 review estimates daily use is associated with a 10-20% rate of dependence. The highest risk of cannabis dependence is found in those with a history of poor academic achievement, deviant behavior in childhood and adolescence, rebelliousness, poor parental relationships, or a parental history of drug and alcohol problems. Of daily users, about 50% experience withdrawal upon cessation of use (i.e. are dependent), characterized by sleep problems, irritability, dysphoria, and craving. Cannabis withdrawal is less severe than withdrawal from alcohol.
The United Kingdom and Germany resumed commercial production in the 1990s. British production is mostly used as bedding for horses; other uses are under development. Companies in Canada, the UK, the United States, and Germany, among many others, process hemp seed into a growing range of food products and cosmetics; many traditional growing countries still continue to produce textile-grade fibre.
More recently, Sakamoto and various co-authors have used RAPD to isolate several genetic marker sequences that they name Male-Associated DNA in Cannabis (MADC), and which they interpret as indirect evidence of a male chromosome. Several other research groups have reported identification of male-associated markers using RAPD and AFLP. Ainsworth commented on these findings, stating,
Due to almost a century of misinformation about Cannabis, the distinction between Cannabis and its two primary species — hemp and marijuana — has become unclear to the many and some even consider the three plants to be one in the same. Because of this, the three terms are often used interchangeably, which has created difficulties when understanding the usage and benefits of Hemp vs Marijuana and Cannabis in general.
The high lipid-solubility of cannabinoids results in their persisting in the body for long periods of time. Even after a single administration of THC, detectable levels of THC can be found in the body for weeks or longer (depending on the amount administered and the sensitivity of the assessment method). A number of investigators have suggested that this is an important factor in marijuana's effects, perhaps because cannabinoids may accumulate in the body, particularly in the lipid membranes of neurons.
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This summary is reviewed regularly and updated as necessary by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH).
Hemp is used in a variety of products we carry. The industrial hemp seed that is used in the products we carry today is not marijuana, although the two are from the same species (Cannabis Sativa). Hemp seeds are sterilized, removing any traces of THC – the mind-altering compound found in the drug. Industrial hemp can be grown with relatively little fertilizer and without the pesticides that have been known to pollute ground water and river systems.
Cannabis use for medicinal purposes dates back at least 3,000 years.[1-5] It was introduced into Western medicine in 1839 by W.B. O’Shaughnessy, a surgeon who learned of its medicinal properties while working in India for the British East India Company. Its use was promoted for reported analgesic, sedative, anti-inflammatory, antispasmodic, and anticonvulsant effects.
Folks. This article has nothing whatsoever to do wiht legalization of marijuana. Why do you keep commenting on legalizing pot, medical or otherwise? This article is about hemp. TOTALLY different. As an agricultural product it is very adaptable, forgiving and has a multitude of uses. Please stay on topic and help to promote the valuable product of HEMP. South Carolina has made it legal to grow and the rest of the country would benefit from following suit. Again, this has absolutely nothing to do with Pot!!!!!
In Buddhism, cannabis is generally regarded as an intoxicant and may be a hindrance to development of meditation and clear awareness. In ancient Germanic culture, Cannabis was associated with the Norse love goddess, Freya. An anointing oil mentioned in Exodus is, by some translators, said to contain Cannabis. Sufis have used Cannabis in a spiritual context since the 13th century CE.
In late 2017, researchers with the University of Guelph in Canada published the first-ever study to document the ideal growing conditions for cannabis. Using liquid organic fertilizer with a PKN ratio of 1.3P–1.7K-4.0N, the experiment tested five increasing rates of fertilization. They also tested two coir-based soil-less growing media, or “substrates.”
Via CB1 receptor activation, THC indirectly increases dopamine release and produces psychotropic effects. Cannabidiol (CBD) also acts as an allosteric modulator of the μ- and δ-opioid receptors. THC also potentiates the effects of the glycine receptors. It is unknown if or how these actions contribute to the effects of cannabis.
Cannabinoids may also contribute to pain modulation through an anti-inflammatory mechanism; a CB2 effect with cannabinoids acting on mast cell receptors to attenuate the release of inflammatory agents, such as histamine and serotonin, and on keratinocytes to enhance the release of analgesic opioids has been described.[45-47] One study reported that the efficacy of synthetic CB1- and CB2-receptor agonists were comparable with the efficacy of morphine in a murine model of tumor pain.
Reproduced with kind permission from the Australian Drug Foundation. References Australian Drug Foundation. Cannabis Facts. Last updated 25 Jan 2012. http://www.druginfo.adf.org.au/drug-facts/cannabis (accessed Jan 2013). Australian Drug Foundation (ADF) Vision: Healthy People, Strong Communities. Mission: Working together to prevent alcohol and other drug problems in communities.Related ArticlesCannabis psychosisUse of cannabis can cause a condition called drug-induced psychosis. Cannabis useCannabis can affect your physical and mental health with heavy cannabis use potentially causing psycCannabis: tolerance and dependenceAfter prolonged use, cannabis is addictive and people using cannabis regularly develop dependence anCannabis: withdrawal and treatmentIf a dependent person stops taking cannabis, they may experience withdrawal symptoms. Cannabis/marijuana: what are the effects?The effect of cannabis on a person depends on many factors including their size, weight and health aAdvertisement
Essential (volatile) oil in hemp is quite different from hempseed oil. Examples of commercial essential oil product products are shown in Fig. 42. The essential oil is a mixture of volatile compounds, including monoterpenes, sesquiterpenes, and other terpenoid-like compounds that are manufactured in the same epidermal glands in which the resin of Cannabis is synthesized (Meier and Mediavilla 1998). Yields are very small—about 10 L/ha (Mediavilla and Steinemann 1997), so essential oil of C. sativa is expensive, and today is simply a novelty. Essential oil of different strains varies considerably in odor, and this may have economic importance in imparting a scent to cosmetics, shampoos, soaps, creams, oils, perfumes, and foodstuffs. Switzerland has been a center for the production of essential oil for the commercial market. Narcotic strains tend to be more attractive in odor than fiber strains, and because they produce much higher numbers of flowers than fiber strains, and the (female) floral parts provide most of the essential oil, narcotic strains are naturally adapted to essential oil production. Switzerland has permitted strains with higher THC content to be grown than is allowed in other parts of the world, giving the country an advantage with respect to the essential oil market. However, essential oil in the marketplace has often been produced from low-THC Cannabis, and the THC content of essential oil obtained by steam distillation can be quite low, producing a product satisfying the needs for very low THC levels in food and other commercial goods. The composition of extracted essential oil is quite different from the volatiles released around the fresh plant (particularly limonene and alpha-pinene), so that a pleasant odor of the living plant is not necessarily indicative of a pleasant-smelling essential oil. Essential oil has been produced in Canada by Gen-X Research Inc., Regina. The world market for hemp essential oil is very limited at present, and probably also has limited growth potential.
Plus CBD Oil™ products come in a variety of flavors and concentrations to suit your preferences. If you are considering CBD oil for your health, as with any supplement, we encourage you to speak with your physician and dive into the research to learn more about this promising phytonutrient. We at Plus CBD Oil™ are proud of our innovative selection of products.
During the period from 1937 to the late 60s, the U.S. government understood and acknowledged that industrial hemp and marijuana were distinct varieties of the Cannabis plant. Hemp was no longer officially recognized as distinct from marijuana after the passage of the Controlled Substances Act (CSA) of 1970. This is despite the fact that a specific exemption for hemp was included in the CSA under the definition of marijuana. The recent federal court case HIA vs DEA has re-established acknowledgement of distinct varieties of Cannabis, and supports the exemption for non-viable seed and fiber and any products made from them.
This is a huge, HUGE step for N.C. First of all farmers can FINALLY make money off land that has grown tobacco for generations. FINALLY doubter I finding out there are many uses for the plant. Perhaps one of the biggest things is the impact on the environment. Most products, if not all, are biodegradable. Also, a huge factor is that in the field of medicine. Will this lead to medical and/or recreational marijuana? Time will tell. As for me, I quit smoking it 20 years ago. I do, however, believe any and all forms of cannabis should and will be made legal. Legal, if for no other reason, so we can stop making people who smoke it into criminals, filling up our jails and prisons. This will free up police, etc.. to finding real criminals. Last, but defiantly not least, IMHO, there is the N.C. aspect. That being I thought we would never, EVER see this time in N.C. Even if it is just industrial hemp for now, it’s a start. Who knows, in the not too distant future, legislatures and law enforcement will become open minded enough to legalize all forms of cannabis, HOPEFULLY. With the youth of these times moving into the right fields, and of course us boomers weighing in, it won’t be too long. AMEN
Epidiolex is the first FDA-approved treatment in the U.S. that contains a purified drug substance derived from marijuana -- CBD -- and the first treatment for Dravet syndrome. In September 2018 the FDA rescheduled cannabidiol from a C-I controlled substance to a C-V controlled substance, meaning it has a proven medical use but a low risk of abuse. This change allows Epidiolex to be marketed in the U.S.
Both in Canada and the US, the most critical problem to be addressed for commercial exploitation of C. sativa is the possible unauthorized drug use of the plant. Indeed, the reason hemp cultivation was made illegal in North America was concern that the hemp crop was a drug menace. The drug potential is, for practical purposes, measured by the presence of THC. THC is the world’s most popular illicit chemical, and indeed the fourth most popular recreational drug, after caffeine, alcohol, and nicotine. “Industrial hemp” is a phrase that has become common to designate hemp used for commercial non-intoxicant purposes. Small and Cronquist (1976) split C. sativa into two subspecies: C. sativa subsp. sativa, with less than 0.3% (dry weight) of THC in the upper (reproductive) part of the plant, and C. sativa subsp. indica (Lam.) E. Small & Cronq. with more than 0.3% THC. This classification has since been adopted in the European Community, Canada, and parts of Australia as a dividing line between cultivars that can be legally cultivated under license and forms that are considered to have too high a drug potential. For a period, 0.3% was also the allowable THC content limit for cultivation of hemp in the Soviet Union. In the US, Drug Enforcement Agency guidelines issued Dec. 7, 1999 expressly allowed products with a THC content of less than 0.3% to enter the US without a license; but subsequently permissible levels have been a source of continuing contention. Marijuana in the illicit market typically has a THC content of 5% to 10% (levels as high as 25% have been reported), and as a point of interest, a current Canadian government experimental medicinal marijuana production contract calls for the production of 6% marijuana. As noted above, a level of about 1% THC is considered the threshold for marijuana to have intoxicating potential, so the 0.3% level is conservative, and some countries (e.g. parts of Australia, Switzerland) have permitted the cultivation of cultivars with higher levels. It should be appreciated that there is considerable variation in THC content in different parts of the plant. THC content increases in the following order: achenes (excluding bracts), roots, large stems, smaller stems, older and larger leaves, younger and smaller leaves, flowers, perigonal bracts covering both the female flowers and fruits. It is well known in the illicit trade how to screen off the more potent fractions of the plant in order to increase THC levels in resultant drug products. Nevertheless, a level of 0.3% THC in the flowering parts of the plant is reflective of material that is too low in intoxicant potential to actually be used practically for illicit production of marijuana or other types of cannabis drugs. Below, the problem of permissible levels of THC in food products made from hempseed is discussed.
A population-based case-control study of 611 lung cancer patients revealed that chronic low Cannabis exposure was not associated with an increased risk of lung cancer or other upper aerodigestive tract cancers and found no positive associations with any cancer type (oral, pharyngeal, laryngeal, lung, or esophagus) when adjusting for several confounders, including cigarette smoking.
One of the biggest players in this new industry is Medical Marijuana, Inc., a company formed in 2009 that operates out of Poway, California, just north of San Diego. It has played a leading role in the so-called Green Rush, as businesses have moved quickly to capitalize on the gradual legalization of marijuana for medical and recreational purposes by states across the country. The company’s spokesman, Andrew Hard, boasted that Medical Marijuana, Inc., “created the CBD industry and was first to market with CBD products.” Through its various subsidiaries, Medical Marijuana, Inc. sells some of the most recognizable products on the cannabis market— everything from Cibaderm CBD-infused shampoo to CanChew chewing gum. In 2014, the company generated $14.5 million in revenue.
Grown and extracted from the USA, our quality CBD is fully compliant under the Kentucky Department of Agricultural Industrial Hemp Pilot Program. Our CBD products are legal and shipped to all 50 states and internationally. All of our CBD products contain 0% THC, guaranteed. We utilize a whole plant CO2 extraction that allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.
At least 50% of patients who receive moderately emetogenic chemotherapy may experience delayed chemotherapy-induced N/V. Although selective neurokinin 1 antagonists that inhibit substance P have been approved for delayed N/V, a study was conducted before their availability to assess dronabinol, ondansetron, or their combination in preventing delayed-onset chemotherapy-induced N/V. Ondansetron, a serotonin 5-hydroxytryptamine 3 (5-HT3) receptor antagonist, is one of the mainstay agents in the current antiemetic armamentarium. In this trial, the primary objective was to assess the response 2 to 5 days after moderately to severely emetogenic chemotherapy. Sixty-one patients were analyzed for efficacy. The total response–a composite endpoint–including nausea intensity, vomiting/retching, and use of rescue medications, was similar with dronabinol (54%), ondansetron (58%), and combination therapy (47%) when compared with placebo (20%). Nausea absence was greater in the active treatment groups (dronabinol 71%, ondansetron 64%, combination therapy 53%) when compared with placebo (15%; P < .05 vs. placebo for all). Occurrence rates for nausea intensity and vomiting/retching episodes were the lowest in patients treated with dronabinol, suggesting that dronabinol compares favorably with ondansetron in this situation where a substance P inhibitor would currently be the drug of choice.
According to the United Nations Office on Drugs and Crime (UNODC), "the amount of THC present in a cannabis sample is generally used as a measure of cannabis potency." The three main forms of cannabis products are the flower, resin (hashish), and oil (hash oil). The UNODC states that cannabis often contains 5% THC content, resin "can contain up to 20% THC content", and that "Cannabis oil may contain more than 60% THC content."
In 1925 a compromise was made at an international conference in The Hague about the International Opium Convention that banned exportation of "Indian hemp" to countries that had prohibited its use, and requiring importing countries to issue certificates approving the importation and stating that the shipment was required "exclusively for medical or scientific purposes". It also required parties to "exercise an effective control of such a nature as to prevent the illicit international traffic in Indian hemp and especially in the resin". In the United States in 1937, the Marihuana Tax Act was passed, and prohibited the production of hemp in addition to cannabis.
Cannabis Indica – The annual plant of the Cannabaceae family is considered a species of the genus Cannabis, but separate from Cannabis sativa, and originating in the Hindu Kush Mountains and suited for cultivation in temperate climates. Used to induce sleep, the plant is described as relatively short and conical with dense branches and short, broad leaves, while Cannabis sativa is tall with fewer branches and long, narrow leaves.
Some studies state that while there is no proof for the gateway hypothesis, young cannabis users should still be considered as a risk group for intervention programs. Other findings indicate that hard drug users are likely to be poly-drug users, and that interventions must address the use of multiple drugs instead of a single hard drug. Almost two-thirds of the poly drug users in the "2009/10 Scottish Crime and Justice Survey" used cannabis.
In the 1970s, President Nixon declared a “War on Drugs” and signed into law the Controlled Substances Act of 1970. This law established a set of banned drugs and created the Drug Enforcement Administration (DEA). It also unintentionally outlawed one of the world’s oldest domesticated crop, hemp. This not only led to the demise of hemp, but also an increased misconception of the plant.
C.S. Lewis said “badness is only spoiled goodness.” This may be an apt quote regarding public perception. It’s true that hemp’s scientific name is the same as that other Cannabis sativa, marijuana, but its constituents are different. The three cannabis plants have three different species: Sativa, used for industrial fibers, oils, food, drugs and medicine; Indica, to induce sleep; and Ruderalis, for food production. Hemp seeds contain high amounts of essential fatty acids – more than any fish and most fish oil supplements. The oil has linoleic acid, alpha-linolenic acid, and at least 20 amino acids. Altogether, hemp supplies innumerable health benefits. After decades of misunderstanding, scientists have again been tapping the amazing potential of this versatile plant.
But, uh, what is it that CBD is supposed to do? I visited a cannabis dispensary in Boulder to find out what the hype was all about. After passing an ID check, I was introduced to a “budtender” who pointed me to an impressive array of CBD products — tinctures, skin patches, drink powders, candies, salves, massage oil, lotions, “sexy time personal intimacy oil” and even vaginal suppositories to treat menstrual cramps.
Jump up ^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.