Jump up ^ Morales, Paula; Hurst, Dow P.; Reggio, Patricia H. (2017). "Molecular Targets of the Phytocannabinoids: A Complex Picture". In Kinghorn, A. Douglas; Falk, Heinz; Gibbons, Simon; Kobayashi, Jun'ichi. Phytocannabinoids: Unraveling the Complex Chemistry and Pharmacology of Cannabis sativa. Progress in the Chemistry of Organic Natural Products. 103. Springer International Publishing. pp. 103–131. doi:10.1007/978-3-319-45541-9_4. ISBN 978-3-319-45539-6. PMC 5345356. PMID 28120232.
The “re-“growth of industrial hemp in the United States is heavily regulated, although the neighbouring nation of Canada successfully grows hemp commercially. Since becoming legal to grow again in Canada, the crop has taken off and has become a booming multi-million dollar export. Hemp building materials are another growing segment of the hemp industry. Canada is now a leader in the global hemp food/health marketplace. Canadian hemp products can be found in many hemp markets now in the United States and the world over.
Cannabis impairs psychomotor performance in a wide variety of tasks, such as motor coordination, divided attention, and operative tasks of many types; human performance on complex machinery can be impaired for as long as 24 hours after smoking as little as 20 mg of THC in cannabis; there is an increased risk of motor vehicle accidents among persons who drive when intoxicated by cannabis.
Most pro-hemp initiatives in the United States are now focused on defining and distinguishing between industrial hemp and marijuana. Some pro-hemp supporters would like to move the control of U.S. hemp production from the DEA to the USDA. Proponents of legalizing hemp also argue that new technology to distinguish THC levels both in the field and from the air will allow for adequate production enforcement.
Canada is specialized on oilseed production and processing, so that hemp oil and grain are much more suitable than fiber. Because of the extensive development of oilseeds in Canada, there is extensive capacity to produce high-quality cold-pressed hemp oil. Canada in the last 5 years has made great advances in the growing, harvesting, and processing of hempseed, and indeed has moved ahead of the EU in the development of raw materials and products for the natural foods, nutraceuticals, and cosmetics industries. In the EU, a yield of 1 t/ha is considered good. In Canada, extraordinary yields of 1.5 t/ha have been realized, at least locally, although in the initial years of hempseed development in Canada yields were often less than 500 kg/ha. In 1999, the year of largest Canadian hemp acreage, yields averaged 900 kg/ha. (Ideally, hemp seed yield should be based on air dry weight—with about 12% moisture. Hemp yields are sometime uncertain, and could be exaggerated by as much as 50% when moist weights are reported.)
PDQ is a registered trademark. Although the content of PDQ documents can be used freely as text, it cannot be identified as an NCI PDQ cancer information summary unless it is presented in its entirety and is regularly updated. However, an author would be permitted to write a sentence such as “NCI’s PDQ cancer information summary about breast cancer prevention states the risks succinctly: [include excerpt from the summary].”
An absence of such fiber-strain traits as tallness, limited branching, long internodes, and very hollow stems, is characteristic of narcotic strains. Drug forms have historically been grown in areas south of the north-temperate zone, often close to the equator, and are photoperiodically adapted to a long season. When grown in north-temperate climates maturation is much-delayed until late fall, or the plants succumb to cold weather before they are able to produce seeds. Unlike fiber strains that have been selected to grow well at extremely high densities, drug strains tend to be less persistent when grown in high concentration (de Meijer 1994). Drug strains can be very similar in appearance to fiber strains. However, a characteristic type of narcotic plant was selected in southern Asia, particularly in India and neighboring countries. This is dioecious, short (about a meter in height), highly branched, with large leaves (i.e. wide leaflets), and it is slow to mature. The appearance is rather like a short, conical Christmas tree.
Even without changes at the federal level, there are steps that states could take on their own to make the CBD market safer. States with broad marijuana legality or CBD-only measures could mandate the calibration and regulation of testing labs, and use them to conduct safety testing. They could fund research into the benefits, dosing, and drug interactions of CBD through their public university systems. Medical boards could redouble efforts to educate physicians in what research exists regarding medical marijuana in all its incarnations, so that doctors are prepared to prescribe and manage these medications as they become available.
Despite its centrality in human cultures across the globe, the European taxonomists who bequeathed Cannabis sativa its name didn’t quite get it right. When Carolus Linneaus came to naming the marijuana plant’s genus, he thought there was only one species, instead of the three we now know exist. Hence the confusion surrounding the fact that there are three distinct species of the genus Cannabis sativa, one of which is the sativa species.
The opportunity to grow a new specialty oilseed crop in Kansas offers potential for diversification for Kansas farmers looking for an alternative crop, or for new farming enterprises interested in cultivating industrial hemp. The Kansas agriculture industry has developed a statewide strategic growth plan in recent years, and is committed to pursuing new and innovative opportunities to grow agriculture. The research generated by participants of this new industrial hemp program will be valuable data in identifying the growth potential offered in this sector.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain. It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12. Although currently classified as orphan receptors, these receptors are most closely related phylogeneticaly to the cannabinoid receptors. In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist, and this action may be involved in its antidepressant, anxiolytic, and neuroprotective effects. It is an allosteric modulator of the μ- and δ-opioid receptors as well. The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.
CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.
Lisa Hamilton, a jeweler and doula in Brooklyn, NY, knows about the side effects. She recently tried CBD for the shoulder pain that plagued her five years after an accident. Her doctor certified that she was in chronic pain, which under New York State law allowed her to buy from a state dispensary. One Friday, she swallowed two 10-mg capsules, the amount recommended at the dispensary, then took another two on Saturday. “By Sunday, it felt like I’d gotten hit by a truck. Every muscle and joint ached,” Hamilton says. She cut back to one pill a day the following week, but still felt hungover. She stopped after that.
One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors. During this 2-year study, groups of mice and rats were given various doses of THC by gavage. A dose-related decrease in the incidence of hepatic adenoma tumors and hepatocellular carcinoma (HCC) was observed in the mice. Decreased incidences of benign tumors (polyps and adenomas) in other organs (mammary gland, uterus, pituitary, testis, and pancreas) were also noted in the rats. In another study, delta-9-THC, delta-8-THC, and cannabinol were found to inhibit the growth of Lewis lung adenocarcinoma cells in vitro and in vivo . In addition, other tumors have been shown to be sensitive to cannabinoid-induced growth inhibition.[5-8]
“Folks at the various state Departments of Agriculture are so excited to bring in hemp – excited to introduce any crop, really, and especially to reintroduce this extraordinarily versatile one,” Beckerman said. “But they’re not experts; they’re learning like anybody else. So getting in there, looking at proposed legislation and rules to make sure [proposals] actually make sense for the crop – on an agronomic level, on a regulatory level – and monitoring changes to that legislation, regulation, or industry, is common sense.” She went on,
Liquid CBD Oil/Tinctures/Extracts: Drops or tinctures should have a “suggested serving size” and the total milligrams of CBD listed on their packaging. From there, you can determine the amount of CBD you would like to ingest. Simply place the correct quantity of drops under your tongue using the dropper and hold the CBD oil in place for a minimum of 60 seconds. The 60 second hold allows for absorption via the blood vessels underneath your tongue – efficiently bypassing first-pass metabolism. Once 60 seconds has passed, swallow the CBD oil.
Over the ages, countless innovations have attempted to improve on the basic experience of inhaling the smoke of combusted cannabis. As a result, there are numerous ways to smoke marijuana. The rolling technique is at the root of joints, blunts, and spliffs. On the other hand, glassware and other devices are essential for smoking weed out of a pipe, bong, or bubbler.
As noted above, hemp seed cake makes an excellent feed for animals. However, feeding entire plants is another matter, because the leaves are covered with the resin-producing glands. While deer, groundhogs, rabbits, and other mammals will nibble on hemp plants, mammals generally do not choose to eat hemp. Jain and Arora (1988) fed narcotic Cannabis refuse to cattle, and found that the animals “suffered variable degrees of depression and revealed incoordination in movement.” By contrast, Letniak et al. (2000) conducted an experimental trial of hemp as silage. No significant differences were found between yield of the hemp and of barley/oat silage fed to heifers, suggesting that fermenting hemp plants reduces possible harmful constituents.
Our award-winning support staff, experienced cultivators, and network of healthcare practitioners are here to help remove barriers to medical cannabis. We’re honoured to be part of a movement that’s helping Canadians across the country access their medicine; and as we grow we will continue to provide patients with reliable access to safe, consistent, and effective medical cannabis.
THC, an intoxicating and illegal substance, is responsible for causing marijuana users to get “high.” Unlike THC, CBD is non-psychoactive because it does not act on the same pathways as THC. Thus, it is impossible to get “high” by smoking or ingesting CBD or CBD oil extracted from industrial hemp plants, as they only have minuscule traces of THC (<0.3%).
Neurologists are skilled at predicting side effects and interactions between well-researched pharmaceuticals. But due to the dearth of reliable research about CBD, doctors like Hernandez and Knupp cannot guide their patients in its use. If there are adverse reactions, Penny will find out because Harper will suffer through them. She has had to figure out through trial and error how best to mix and measure Harper’s oils. The bottom line, Penny said, is simple: “We are the research.”
Hemp paper is useful for specialty applications such as currency and cigarette papers where strength is needed. The bast fiber is of greatest interest to the pulp and paper industry because of its superior strength properties compared to wood. However, the short, bulky fibers found in the inner part of the plant (hurds) can also be used to make cheaper grades of paper, apparently without greatly affecting quality of the printing surface. Hemp is not competitive for newsprint, books, writing papers, and general paper (grocery bags, coffee cups, napkins), although there is a specialty or novelty market for those specifically wishing to support the hemp industry by purchasing hemp writing or printing paper despite the premium price (Fig. 17).
Did you get an answer for this? I have the exact same scenario. I'm treating my TN with Tegretol, and recently tried CBD. I think I took too much and there are some weird drug interactions with Tegretol and I felt quite stoned....was alone and talking to myself in my head thinking I was Einstein. It freaked me out a bit but I think I took too much. I'm trying lower doses again as recently my TN seems to be resisting the meds, although I have had a lot of emotional stress, which seems to be a trigger. Thanks!! Anna
One of the reasons hemp fiber has been valued is because of its length. The primary bast fibers in the bark are 5–40 mm long, and are amalgamated in fiber bundles which can be 1–5 m long (secondary bast fibers are about 2 mm long). The woody core fibers are short—about 0.55 mm—and like hardwood fibers are cemented together with considerable lignin. The core fibers are generally considered too short for high grade paper applications (a length of 3 mm is considered ideal), and too much lignin is present. While the long bast fibers have been used to make paper almost for 2 millennia, the woody core fibers have rarely been so used. Nevertheless it has been suggested that the core fibers could be used for paper making, providing appropriate technology was developed (de Groot et al. 1998). In any event, the core fibers, have found a variety of uses, as detailed below. The long, lignin-poor bast fibers also have considerable potential to be used in many non-paper, non-textile applications, as noted below.
From 1982 to 2002 the EU provided the equivalent of about 50 million dollars to develop new flax and hemp harvesting and fiber processing technologies (Karus et al. 2000). Because of the similarities of flax and hemp, the technologies developed for one usually are adaptable to the other. In addition, various European nations and private firms contributed to the development of hemp technologies. Accordingly, Europe is far more advanced in hemp development with respect to all fiber-based applications than other parts of the world. The EU currently dedicates about 30,000 ha to hemp production. France is the leading country in hemp cultivation in the EU, and 95% of the non-seed production is used for “specialty pulp” as described below. Harvesting and processing machinery for fiber hemp is highly advanced in Europe, and some has been imported into Canada. However, there is insufficient fiber processing capacity to handle hemp produced in Canada.
Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, to treat disease or improve symptoms. Cannabis is used to reduce nausea and vomiting during chemotherapy, to improve appetite in people with HIV/AIDS, and to treat chronic pain and muscle spasms. Cannabinoids are under preliminary research for their potential to affect stroke.
There is some speculation that George Washington smoked the flower of the cannabis plant in order to achieve a recreational high ("Like all farmers, Washington probably sampled the quality and potency of what he grew, and he may have used this hemp to treat his chronic tooth aches"), but there is no evidence in any of his writings that he grew hemp for anything other than industrial purposes. It is sometimes supposed that an excerpt from Washington's diary, which reads "Began to seperate [sic] the Male from the Female hemp at Do.&—rather too late" is evidence that he was trying to grow female plants for the THC found in the flowers. However, the editorial remark accompanying the diary states that "This may arise from their [the male] being coarser, and the stalks larger" In subsequent days, he describes soaking the hemp (to make the fibers usable) and harvesting the seeds, suggesting that he was growing hemp for industrial purposes, not recreational.
One of the biggest players in this new industry is Medical Marijuana, Inc., a company formed in 2009 that operates out of Poway, California, just north of San Diego. It has played a leading role in the so-called Green Rush, as businesses have moved quickly to capitalize on the gradual legalization of marijuana for medical and recreational purposes by states across the country. The company’s spokesman, Andrew Hard, boasted that Medical Marijuana, Inc., “created the CBD industry and was first to market with CBD products.” Through its various subsidiaries, Medical Marijuana, Inc. sells some of the most recognizable products on the cannabis market— everything from Cibaderm CBD-infused shampoo to CanChew chewing gum. In 2014, the company generated $14.5 million in revenue.
This is a huge, HUGE step for N.C. First of all farmers can FINALLY make money off land that has grown tobacco for generations. FINALLY doubter I finding out there are many uses for the plant. Perhaps one of the biggest things is the impact on the environment. Most products, if not all, are biodegradable. Also, a huge factor is that in the field of medicine. Will this lead to medical and/or recreational marijuana? Time will tell. As for me, I quit smoking it 20 years ago. I do, however, believe any and all forms of cannabis should and will be made legal. Legal, if for no other reason, so we can stop making people who smoke it into criminals, filling up our jails and prisons. This will free up police, etc.. to finding real criminals. Last, but defiantly not least, IMHO, there is the N.C. aspect. That being I thought we would never, EVER see this time in N.C. Even if it is just industrial hemp for now, it’s a start. Who knows, in the not too distant future, legislatures and law enforcement will become open minded enough to legalize all forms of cannabis, HOPEFULLY. With the youth of these times moving into the right fields, and of course us boomers weighing in, it won’t be too long. AMEN
Jump up ^ McLaren JA, Silins E, Hutchinson D, Mattick RP, Hall W (January 2010). "Assessing evidence for a causal link between cannabis and psychosis: a review of cohort studies". The International Journal on Drug Policy. 21 (1): 10–9. doi:10.1016/j.drugpo.2009.09.001. PMID 19783132. The contentious issue of whether cannabis use can cause serious psychotic disorders that would not otherwise have occurred cannot be answered based on the existing data
“The plan? Whip the public into a frenzy over ill effects of marijuana, the psychoactive leaves and flowers of the hemp plant; the reputation of the fibers and seeds used by industry would be posing little threat to society emerged as the ‘assassin of youth.’ The strategy worked. In 1937, with virtually no warning, Congress announced a prohibitive tax on hemp, effectively ending the production and sale of the plant in the United States.
The main psychoactive constituent of Cannabis was identified as delta-9-tetrahydrocannabinol (THC). In 1986, an isomer of synthetic delta-9-THC in sesame oil was licensed and approved for the treatment of chemotherapy -associated nausea and vomiting under the generic name dronabinol. Clinical trials determined that dronabinol was as effective as or better than other antiemetic agents available at the time. Dronabinol was also studied for its ability to stimulate weight gain in patients with AIDS in the late 1980s. Thus, the indications were expanded to include treatment of anorexia associated with human immunodeficiency virus infection in 1992. Clinical trial results showed no statistically significant weight gain, although patients reported an improvement in appetite.[9,10] Another important cannabinoid found in Cannabis is CBD. This is a nonpsychoactive cannabinoid, which is an analog of THC.
As marijuana is legalized in more and more states, the wellness world has whipped itself into a frenzy over a non-intoxicating cannabis derivative called cannabidiol. CBD products can be found on the internet and in health-food stores, wellness catalogs and even bookstores. (A bookstore in downtown Boulder, Colorado, displays a case of CBD products between the cash register and the stacks of new releases.) Celebrities like Gwyneth Paltrow, disgraced cyclist1 Floyd Landis and former Denver Broncos quarterback Jake Plummer are all touting CBD products, and according to Bon Appétit, CBD-infused lattes have become “the wellness world’s new favorite drink.”
Plastic composites for automobiles are the second most important component of the hemp industry of the EU. Natural fibers in automobile composites are used primarily in press-molded parts (Fig. 18). There are two widespread technologies. In thermoplastic production, natural fibers are blended with polypropylene fibers and formed into a mat, which is pressed under heat into the desired form. In thermoset production the natural fibers are soaked with binders such as epoxy resin or polyurethane, placed in the desired form, and allowed to harden through polymerization. Hemp has also been used in other types of thermoplastic applications, including injection molding. The characteristics of hemp fibers have proven to be superior for production of molded composites. In European manufacturing of cars, natural fibers are used to reinforce door panels, passenger rear decks, trunk linings, and pillars. In 1999 over 20,000 t of natural fiber were used for these purposes in Europe, including about, 2,000 t of hemp. It has been estimated that 5–10 kg of natural fibers can be used in the molded portions of an average automobile (excluding upholstery). The demand for automobile applications of hemp is expected to increase considerably, depending on the development of new technologies (Karus et al. 2000).
Put simply, “indica” strains are those associated with a strong body-high, feelings of sedation and relaxation. For this reason, indicas are often thought of as the “heavier” strains of cannabis, offering stronger highs that impact the whole body. They’re popular among marijuana users as pain relieving and sleep-inducing strains. Indicas are especially popular among medical cannabis patients.
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We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
Karl W. Hillig, a graduate student in the laboratory of long-time Cannabis researcher Paul G. Mahlberg at Indiana University, conducted a systematic investigation of genetic, morphological, and chemotaxonomic variation among 157 Cannabis accessions of known geographic origin, including fiber, drug, and feral populations. In 2004, Hillig and Mahlberg published a chemotaxonomic analysis of cannabinoid variation in their Cannabis germplasm collection. They used gas chromatography to determine cannabinoid content and to infer allele frequencies of the gene that controls CBD and THC production within the studied populations, and concluded that the patterns of cannabinoid variation support recognition of C. sativa and C. indica as separate species, but not C. ruderalis. The authors assigned fiber/seed landraces and feral populations from Europe, Central Asia, and Turkey to C. sativa. Narrow-leaflet and wide-leaflet drug accessions, southern and eastern Asian hemp accessions, and feral Himalayan populations were assigned to C. indica. In 2005, Hillig published a genetic analysis of the same set of accessions (this paper was the first in the series, but was delayed in publication), and proposed a three-species classification, recognizing C. sativa, C. indica, and (tentatively) C. ruderalis. In his doctoral dissertation published the same year, Hillig stated that principal components analysis of phenotypic (morphological) traits failed to differentiate the putative species, but that canonical variates analysis resulted in a high degree of discrimination of the putative species and infraspecific taxa. Another paper in the series on chemotaxonomic variation in the terpenoid content of the essential oil of Cannabis revealed that several wide-leaflet drug strains in the collection had relatively high levels of certain sesquiterpene alcohols, including guaiol and isomers of eudesmol, that set them apart from the other putative taxa. Hillig concluded that the patterns of genetic, morphological, and chemotaxonomic variation support recognition of C. sativa and C. indica as separate species. He also concluded there is little support to treat C. ruderalis as a separate species from C. sativa at this time, but more research on wild and weedy populations is needed because they were underrepresented in their collection.
Donald Abrams was a member of the committee that reviewed the evidence that went into producing the report, and he said that the studies they reviewed overwhelmingly used pharmaceutically available preparations that contain THC, including dronabinol, nabilone and the whole-plant extract spray nabiximols, which contains equal parts CBD and THC. It’s impossible to know whether the benefits of cannabis can also be obtained from CBD alone, Abrams said, because CBD is just one of 400 chemicals present in the plant. So far, CBD in isolation has been studied in only a handful of randomized, placebo-controlled trials (considered the gold standard of evidence in medical research), and the evidence remains sparse.
If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.
In the United States, the legality of medical marijuana varies in substantial ways from state to state. There are currently 29 US states with legal medical cannabis laws, as well as the District of Columbia. That leaves 21 states where medical marijuana is entirely prohibited. Marijuana cultivation, possession, and use in any form is illegal at the federal level.
Rather than keeping people out of the industry, Money thinks regulators should focus on helping farmers sell their products: for example, by connecting them with the "biomass brokers" who deal in the fibers, stalks, and seed matter produced by industrial hemp. "What I'm finding is that a lot of farmers in Wisconsin don't know what to do with their products," she said. "We tried to get a list of licensed farmers to help connect them with brokers, but the state wouldn't release that list."
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
Textile expert Elizabeth Wayland Barber summarizes the historical evidence that Cannabis sativa, "grew and was known in the Neolithic period all across the northern latitudes, from Europe (Germany, Switzerland, Austria, Romania, Ukraine) to East Asia (Tibet and China)," but, "textile use of Cannabis sativa does not surface for certain in the West until relatively late, namely the Iron Age." "I strongly suspect, however, that what catapulted hemp to sudden fame and fortune as a cultigen and caused it to spread rapidly westwards in the first millennium B.C. was the spread of the habit of pot-smoking from somewhere in south-central Asia, where the drug-bearing variety of the plant originally occurred. The linguistic evidence strongly supports this theory, both as to time and direction of spread and as to cause."
The Drug Enforcement Agency and the Office of National Drug Control Policy of the US raised concerns over tests conducted from 1995 to 1997 that showed that consumption of hempseed products available during that period led to interference with drug-testing programs for marijuana use. Federal US programs utilize a THC metabolite level of 50 parts per billion in urine. Leson (2000) found that this level was not exceeded by consuming hemp products, provided that THC levels are maintained below 5 ppm in hemp oil, and below 2 ppm in hulled seeds. Nevertheless the presence of even minute trace amounts of THC in foods remains a tool that can be used by those wishing to prevent the hemp oilseed industry from developing.
Jump up ^ Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA (June 2012). "Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective". Drug and Alcohol Dependence (Review). 123 Suppl 1: S3–17. doi:10.1016/j.drugalcdep.2011.12.018. PMC 3600369. PMID 22261179.
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders. Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions. This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content. Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.
Several studies have demonstrated the therapeutic effects of cannabinoids for nausea and vomiting in the advanced stages of illnesses such as cancer and AIDS. Dronabinol (tetrahydrocannabinol) has been available by prescription for more than a decade in the USA. Other therapeutic uses of cannabinoids are being demonstrated by controlled studies, including treatment of asthma and glaucoma, as an antidepressant, appetite stimulant, anticonvulsant and anti-spasmodic, research in this area should continue. For example, more basic research on the central and peripheral mechanisms of the effects of cannabinoids on gastrointestinal function may improve the ability to alleviate nausea and emesis. More research is needed on the basic neuropharmacology of THC and other cannabinoids so that better therapeutic agents can be found.
In Buddhism, cannabis is generally regarded as an intoxicant and may be a hindrance to development of meditation and clear awareness. In ancient Germanic culture, Cannabis was associated with the Norse love goddess, Freya. An anointing oil mentioned in Exodus is, by some translators, said to contain Cannabis. Sufis have used Cannabis in a spiritual context since the 13th century CE.
There are ways to strain dangerous contaminants out of raw hemp paste. And most companies stand behind their quality and safety procedures. “We continuously test all our products ... to ensure our consumers get the levels of natural constituents they expect from the quality hemp stalk oil they purchase,” HempMedsPx states on its web site. “Additionally, all our products are tested for safety, to ensure there are no solvents, heavy metals, or other potentially harmful materials in our oil. Because we take these steps, we are always confident in our products, and you can be too.”