Yet the DEA has stated unequivocally that it considers CBD to be illegal under the Controlled Substances Act. “CBD derived from the cannabis plant is controlled under Schedule I of the CSA because it is a naturally occurring constituent of marijuana,” Joseph Rannazzisi, the deputy assistant administrator of the DEA, told a congressional panel in June. “While there is ongoing research into a potential medical use of CBD, at this time, CBD has no currently accepted medical use in the USA.” Moreover, DEA spokesman Eduardo Chavez told the New Republic that Medical Marijuana, Inc.’s in-house opinion with regards to CBD has no merit. “The bottom line,” Chavez said, “is the oil is part of the marijuana plant, and the marijuana plant is currently a Schedule I controlled substance under federal law.”
There are also other difficulties in researching the effects of cannabis. Many people who smoke cannabis also smoke tobacco. This causes confounding factors, where questions arise as to whether the tobacco, the cannabis, or both that have caused a cancer. Another difficulty researchers have is in recruiting people who smoke cannabis into studies. Because cannabis is an illegal drug in many countries, people may be reluctant to take part in research, and if they do agree to take part, they may not say how much cannabis they actually smoke.
As in Los Angeles' equity program, the group will offer participants mentorship, job placement, and help with starting businesses in Wisconsin's hemp industry, where close to 220 hemp licenses have already been issued under the current Farm Bill; they also plan to provide on-site housing for participants struggling with homelessness, which often impacts veterans and those recently released from prison.
Highly selected forms of the fiber cultigen possess features maximizing fiber production. Since the nodes tend to disrupt the length of the fiber bundles, thereby limiting quality, tall, relatively unbranched plants with long internodes have been selected. Another strategy has been to select stems that are hollow at the internodes, with limited wood, since this maximizes production of fiber in relation to supporting woody tissues. Similarly, limited seed productivity concentrates the plant’s energy into production of fiber, and fiber cultivars often have low genetic propensity for seed output. Selecting monoecious strains overcomes the problem of differential maturation times and quality of male (staminate) and female (pistillate) plants (males mature 1–3 weeks earlier). Male plants in general are taller, albeit slimmer, less robust, and less productive. Except for the troublesome characteristic of dying after anthesis, male traits are favored for fiber production, in contrast to the situation for drug strains noted below. In former, labor-intensive times, the male plants were harvested earlier than the females, to produce superior fiber. The limited branching of fiber cultivars is often compensated for by possession of large leaves with wide leaflets, which obviously increase the photosynthetic ability of the plants. Since fiber plants have not generally been selected for narcotic purposes, the level of intoxicating constituents is usually limited.
Because C. sativa has been a neglected crop for so long in North America, there are only negligible genetic resources available on this continent. Most germplasm stocks of hemp are in Europe, and the largest and most important collection is the Vavilov Institute gene bank in Leningrad. Figure 11 shows THC concentrations in the Vavilov collection, as well as in our own collection, largely of European germplasm. A disturbingly high percentage of the collections have THC levels higher than 0.3%, making it difficult to incorporate these into breeding programs.
By 1938, Popular Mechanics called hemp the “Billion Dollar Crop,”1 praising its potential to produce 25,000 different products, as high as $192 billion in today’s market and capable of producing four times the paper per acre than trees. Farmers from the Midwest to the East coast harvested more than 150,000 acres for the war’s Hemp for Victory Program, implemented by the USDA from 1942 through 1946, but rumblings by the competition had already started.
Jump up ^ McLaren JA, Silins E, Hutchinson D, Mattick RP, Hall W (January 2010). "Assessing evidence for a causal link between cannabis and psychosis: a review of cohort studies". The International Journal on Drug Policy. 21 (1): 10–9. doi:10.1016/j.drugpo.2009.09.001. PMID 19783132. The contentious issue of whether cannabis use can cause serious psychotic disorders that would not otherwise have occurred cannot be answered based on the existing data
Dosage is important, because CBD can have side effects—the most common are tiredness, diarrhea, and changes in appetite and weight—so it’s best not to take more than you need. As CBD becomes more prevalent, says J. Michael Bostwick, M.D., a psychiatrist at Mayo Clinic in Rochester, MN, “I’m reasonably certain new kinds of side effects will emerge.”
The question of whether heteromorphic sex chromosomes are indeed present is most conveniently answered if such chromosomes were clearly visible in a karyotype. Cannabis was one of the first plant species to be karyotyped; however, this was in a period when karyotype preparation was primitive by modern standards (see History of Cytogenetics). Heteromorphic sex chromosomes were reported to occur in staminate individuals of dioecious "Kentucky" hemp, but were not found in pistillate individuals of the same variety. Dioecious "Kentucky" hemp was assumed to use an XY mechanism. Heterosomes were not observed in analyzed individuals of monoecious "Kentucky" hemp, nor in an unidentified German cultivar. These varieties were assumed to have sex chromosome composition XX. According to other researchers, no modern karyotype of Cannabis had been published as of 1996. Proponents of the XY system state that Y chromosome is slightly larger than the X, but difficult to differentiate cytologically.
The use of Cannabis as a mind-altering drug has been documented by archaeological finds in prehistoric societies in Eurasia and Africa. The oldest written record of cannabis usage is the Greek historian Herodotus's reference to the central Eurasian Scythians taking cannabis steam baths. His (c. 440 BCE) Histories records, "The Scythians, as I said, take some of this hemp-seed [presumably, flowers], and, creeping under the felt coverings, throw it upon the red-hot stones; immediately it smokes, and gives out such a vapour as no Grecian vapour-bath can exceed; the Scyths, delighted, shout for joy." Classical Greeks and Romans were using cannabis, while in the Middle East, use spread throughout the Islamic empire to North Africa. In 1545, cannabis spread to the western hemisphere where Spaniards imported it to Chile for its use as fiber. In North America, cannabis, in the form of hemp, was grown for use in rope, clothing and paper.
Another claim is that Mellon, Secretary of the Treasury and the wealthiest man in America at that time, had invested heavily in DuPont's new synthetic fiber, nylon, and believed[dubious – discuss] that the replacement of the traditional resource, hemp, was integral to the new product's success. The company DuPont and many industrial historians dispute a link between nylon and hemp, nylon became immediately a scarce commodity.[clarification needed] Nylon had characteristics that could be used for toothbrushes (sold from 1938) and very thin nylon fiber could compete with silk and rayon in various textiles normally not produced from hemp fiber, such as very thin stockings for women.
Pinfold Consulting. 1998. (G. Pinfold Consulting Economists Ltd. and J. White, InfoResults Ltd.). A maritime industrial hemp product marketing study. Prepared for Nova Scotia Agriculture and Marketing (Marketing and Food Industry Development), and New Brunswick Agriculture & Rural Development (Marketing and Business Development). agri.gov.ns.ca/pt/agron/hemp/hempms.htm
In Canada, the methodology used for analyses and sample collection for THC analysis of hemp plantings is standardized (at the Health Canada/Therapeutics Program/Hemp web site at www.hc-sc.gc.ca/hpb-dgps/therapeut/htmleng/hemp.html, see “Industrial Hemp Technical Manual” for procedures on sampling plant materials and chemical procedures for determining THC levels). The regulations require that one of the dozen independent laboratories licensed for the purpose conduct the analyses and report the results to Health Canada. Sample collection is also normally carried out by an independent authorized firm. The Canadian system of monitoring THC content has rigidly limited hemp cultivation to cultivars that consistently develop THC levels below 0.3%.
Cannabis has long had an image problem, because of the extremely widespread use of “narcotic” cultivars as illegal intoxicants. The US Drug Enforcement Administration has the mandate of eliminating illicit and wild marijuana, which it does very well (Fig. 54–56). Those interested in establishing and developing legitimate industries based on fiber and oilseed applications have had to struggle against considerable opposition from many in the political and law enforcement arenas. The United States National Institute on Drug Abuse (NIDA) information web site on marijuana, which reflects a negative view of cannabis, is at www.nida.nih.gov/DrugPages/Marijuana.html, and reflects several basic fears: (1) growing Cannabis plants makes law enforcement more difficult, because of the need to ensure that all plants cultivated are legitimate; (2) utilization of legitimate Cannabis products makes it much more difficult to maintain the image of the illegitimate products as dangerous; (3) many in the movements backing development of hemp are doing so as a subterfuge to promote legalization of recreational use of marijuana; and (4) THC (and perhaps other constituents) in Cannabis are so harmful that their presence in any amount in any material (food, medicine or even fiber product) represents a health hazard that is best dealt with by a total proscription.
It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.
Everything you need to know about marijuana (cannabis) Marijuana, or cannabis, is the most commonly used illicit drug in the world. It alters the mood and affects nearly every organ in the body. With at least 120 active compounds, marijuana may have health benefits as well as risks. We describe these, addiction, and withdrawal. Learn more about cannabis here. Read now
My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?
Jews living in Palestine in the 2nd century were familiar with the cultivation of hemp, as witnessed by a reference to it in the Mishna (Kil'ayim 2:5) as a variety of plant, along with Arum, that sometimes takes as many as three years to grow from a seedling. In late medieval Germany and Italy, hemp was employed in cooked dishes, as filling in pies and tortes, or boiled in a soup. Hemp in later Europe was mainly cultivated for its fibers, and was used for ropes on many ships, including those of Christopher Columbus. The use of hemp as a cloth was centered largely in the countryside, with higher quality textiles being available in the towns.
"Right now, any claims and dosing recommendations by any company making a CBD product for the medical marijuana market is purely anecdotal," he says. "Asking 100 people who use your product whether they feel better isn't real science. The products on the market are also different from what was used in the scientific studies that they are basing their claims upon. If a study found an anti-anxiety effect when dosing humans with synthetic CBD, that doesn't mean that your CBD oil that contains 18 percent CBD is going to reduce anxiety. It might even have the opposite effect."
Cannabis sativa L. subsp. sativa var. sativa is the variety grown for industrial use, while C. sativa subsp. indica generally has poor fiber quality and female buds from this variety are primarily used for recreational and medicinal purposes. The major differences between the two types of plants are the appearance, and the amount of Δ9-tetrahydrocannabinol (THC) secreted in a resinous mixture by epidermal hairs called glandular trichomes, although they can also be distinguished genetically. Oilseed and fiber varieties of Cannabis approved for industrial hemp production produce only minute amounts of this psychoactive drug, not enough for any physical or psychological effects. Typically, hemp contains below 0.3% THC, while cultivars of Cannabis grown for medicinal or recreational use can contain anywhere from 2% to over 20%.
“Folks at the various state Departments of Agriculture are so excited to bring in hemp – excited to introduce any crop, really, and especially to reintroduce this extraordinarily versatile one,” Beckerman said. “But they’re not experts; they’re learning like anybody else. So getting in there, looking at proposed legislation and rules to make sure [proposals] actually make sense for the crop – on an agronomic level, on a regulatory level – and monitoring changes to that legislation, regulation, or industry, is common sense.” She went on,
Air-dried stem yields in Ontario have from 1998 and onward ranged from 2.6-14.0 tonnes of dry, retted stalks per hectare (1-5.5 t/ac) at 12% moisture. Yields in Kent County, have averaged 8.75 t/ha (3.5 t/ac). Northern Ontario crops averaged 6.1 t/ha (2.5 t/ac) in 1998. Statistic for the European Union for 2008 to 2010 say that the average yield of hemp straw has varied between 6.3 and 7.3 ton per ha. Only a part of that is bast fiber. Around one tonne of bast fiber and 2-3 tonnes of core material can be decorticated from 3-4 tonnes of good-quality, dry-retted straw. For an annual yield of this level is it in Ontario recommended to add nitrogen (N):70–110 kg/ha, phosphate (P2O5): up to 80 kg/ha and potash (K2O): 40–90 kg/ha. The average yield of dry hemp stalks in Europe was 6 ton/ha (2.4 ton/ac) in 2001 and 2002.
The high lipid-solubility of cannabinoids results in their persisting in the body for long periods of time. Even after a single administration of THC, detectable levels of THC can be found in the body for weeks or longer (depending on the amount administered and the sensitivity of the assessment method). A number of investigators have suggested that this is an important factor in marijuana's effects, perhaps because cannabinoids may accumulate in the body, particularly in the lipid membranes of neurons.
Retting is generally done in the field (Fig. 46, 47). This typically requires weeks. The windrows should be turned once or twice. If not turned, the stems close to the ground will remain green while the top ones are retted and turn brown. When the stalks have become sufficiently retted requires experience—the fibers should have turned golden or grayish in color, and should separate easily from the interior wood. Baling can be done with any kind of baler (Fig. 48). Stalks should have less than 15% moisture when baled, and should be allowed to dry to about 10% in storage. Bales must be stored indoors. Retted stalks are loosely held together, and for highest quality fiber applications need to be decorticated, scutched, hackled, and combed to remove the remaining pieces of stalks, broken fibers, and extraneous material. The equipment for this is rare in North America, and consequently use of domestically-produced fiber for high quality textile applications is extremely limited. However, as described above relatively crude fiber preparations also have applications.
Our custom-designed cultivation facility was built with quality in mind. Instead of a vast, open-air facility we opted to build smaller, laboratory-grade growing rooms. This allows for optimal conditions for each strain, and guarantees that we always have a steady supply of fresh stock. We also follow strict quality control procedures to ensure purity, quality, and customer satisfaction.
Synthetic cannabis is illegal in New Zealand. It is designed to imitate the effects of cannabis and is usually dried plant material sprayed with chemicals known as synthetic cannabinoids. It is also available in liquid form. Little is known about the chemicals used in synthetic cannabis and the effects can be unpredictable, especially when mixed with other substances.
Cannabis plants can be male, female, or hermaphrodite. The dried marijuana flowers that humans consume, however, come from the female plant. That’s because female plants produce large resin-secreting flowers that are rich in cannabinoids and free of seeds. Hence, female plants are the ones growers prefer, though of course, male marijuana plants are a requirement for pollination.
Ten trials have evaluated the efficacy of inhaled Cannabis in chemotherapy-induced N/V.[35-38] In two of the studies, inhaled Cannabis was made available only after dronabinol failure. In the first trial, no antiemetic effect was achieved with marijuana in patients receiving cyclophosphamide or doxorubicin, but in the second trial, a statistically significant superior antiemetic effect of inhaled Cannabis versus placebo was found among patients receiving high-dose methotrexate. The third trial was a randomized, double-blind, placebo-controlled, crossover trial involving 20 adults in which both inhaled marijuana and oral THC were evaluated. One-quarter of the patients reported a favorable antiemetic response to the cannabinoid therapies. This latter study was reported in abstract form in 1984. A full report, detailing the methods and outcomes apparently has not been published, which limits a thorough interpretation of the significance of these findings.
Put simply, “indica” strains are those associated with a strong body-high, feelings of sedation and relaxation. For this reason, indicas are often thought of as the “heavier” strains of cannabis, offering stronger highs that impact the whole body. They’re popular among marijuana users as pain relieving and sleep-inducing strains. Indicas are especially popular among medical cannabis patients.
In the meantime, some physicians are forging ahead — and cashing in. Joe Cohen is a doctor at Holos Health, a medical marijuana clinic in Boulder. I asked him what CBD is good for, and he read me a long list of conditions: pain, inflammation, nausea, vomiting, intestinal cramping, anxiety, psychosis, muscle spasms, hyperactive immune systems, nervous system degeneration, elevated blood sugar and more. He also claimed that CBD has anti-cancer properties and can regenerate brain cells and reduce the brain’s levels of amyloid beta — a kind of protein that’s been linked to Alzheimer’s disease. I asked for references, noting that most of these weren’t listed in the Academies report or a similar review published in the Journal of the American Medical Association. “I think you just have to Google search it,” he said. It’s true that a preliminary study found hints that cannabinoids might reduce beta amyloid proteins in human brain cells, but the study was done in cells grown in a lab, not in people. As for cancer, the FDA sent warning letters last year to four companies that were selling products that claimed to “prevent, diagnose, treat or cure” cancer.
Still, as the saying goes, absence of evidence isn’t necessarily evidence of absence, and there’s a reason we don’t have a ton of solid research on CBDs yet — “to study it, we need a good source, ” said Ziva Cooper, who is an associate professor at Columbia University and was on the National Academies committee. CBD is hard to get because it’s still technically a Schedule I drug, which limits its availability, Cooper said.
It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.
Cannabis was also known to the ancient Assyrians, who discovered its psychoactive properties through the Iranians. Using it in some religious ceremonies, they called it qunubu (meaning "way to produce smoke"), a probable origin of the modern word "cannabis". The Iranians also introduced cannabis to the Scythians, Thracians and Dacians, whose shamans (the kapnobatai—"those who walk on smoke/clouds") burned cannabis flowers to induce trance.
Hemp crops are tall, have thick foliage, and can be planted densely, and thus can be grown as a smother crop to kill tough weeds. Using hemp this way can help farmers avoid the use of herbicides, gain organic certification, and gain the benefits of crop rotation. However, due to the plant's rapid and dense growth characteristics, some jurisdictions consider hemp a prohibited and noxious weed, much like Scotch Broom.