Hemp, Canabis sativa is a plant originally from central Asia. It was cultivated with, and sometimes in place of flax because the stem fibers are similar. By the seventeenth century, Russia, Latvia, and other countries around the Baltic Sea were the major producers of hemp. It was from these areas Britain obtained its supply. However, during periods of military hostilities, the English had trouble acquiring enough hemp.
Those warning letters aside, there’s not a lot of federal oversight right now over the claims being made or the products that are being sold. Cohen warned against buying CBD products online, because “there’s a lot of scams out there.” Yet his clinic sells CBD, and he admits, “I say ‘Don’t buy online,’ but ours is worth doing, because we know what we’re doing. We ship all over.”
The CBD oil needs to be taken twice a day everyday. The dosage depends on symptoms and it takes 30 days to awken your natural cannabis system after you begin taking the oil. I personally use Hemp works CBD oil in the 750 strength and only need 5 drops sublingual 2 times daily and results are many. Problem with oil and alz.patients is getting them to hold oil under tongue for 60 seconds. We have just began to get my dad on it. He too is in a nursing home in the state of florida and they cannot deny him any medication my mom has requested that he receive. If she is not their they are supposed to administer and she will call them to make sure he gets it. He is not 30 days into dosing yet so I don't have any results to speak of. I do know that since he has started he has had no more bladder infection and has not fallen in 3 weeks. That's a record for him so we will continue to monitor. Best of luck to you and a lot is going to depend on the state your mom is in and what the state laws are concerning her rights or the rights of whom has her medical power of attorney
Highly selected forms of the fiber cultigen possess features maximizing fiber production. Since the nodes tend to disrupt the length of the fiber bundles, thereby limiting quality, tall, relatively unbranched plants with long internodes have been selected. Another strategy has been to select stems that are hollow at the internodes, with limited wood, since this maximizes production of fiber in relation to supporting woody tissues. Similarly, limited seed productivity concentrates the plant’s energy into production of fiber, and fiber cultivars often have low genetic propensity for seed output. Selecting monoecious strains overcomes the problem of differential maturation times and quality of male (staminate) and female (pistillate) plants (males mature 1–3 weeks earlier). Male plants in general are taller, albeit slimmer, less robust, and less productive. Except for the troublesome characteristic of dying after anthesis, male traits are favored for fiber production, in contrast to the situation for drug strains noted below. In former, labor-intensive times, the male plants were harvested earlier than the females, to produce superior fiber. The limited branching of fiber cultivars is often compensated for by possession of large leaves with wide leaflets, which obviously increase the photosynthetic ability of the plants. Since fiber plants have not generally been selected for narcotic purposes, the level of intoxicating constituents is usually limited.
Short-term use of the drug impairs thinking and coordination. In long-term studies, teens who smoke marijuana have lower IQs later on, as well as structural differences in their brains, though scientists debate whether this is an effect of the drug or a result of habitual pot smokers seeking out less intellectually stimulating pursuits. A 2016 study on almost 300 students by the University of Montreal published in the journal Development and Psychopathology found that teens who start smoking around age 14 do worse on some cognitive tests by age 20 than non-smokers. They also have a higher school dropout rate. If they wait until age 17 to start, though, the smokers do not seem to have the same impairments, according to the study. 
Settlements which date from c. 2200–1700 BCE in the Bactria and Margiana contained elaborate ritual structures with rooms containing everything needed for making drinks containing extracts from poppy (opium), hemp (cannabis), and ephedra (which contains ephedrine).[113] Although there is no evidence of ephedra being used by steppe tribes, they engaged in cultic use of hemp. Cultic use ranged from Romania to the Yenisei River and had begun by 3rd millennium BC Smoking hemp has been found at Pazyryk.[114]
Dr. Ethan Russo, medical director at Phytecs, a biotechnology company spearheading research into plant- based medicines and the endocannabinoid system, took issue with Titus’s claim, however. “Bioaccumulators can recruit heavy metals from the soil,” Russo said, “but breaking them down would be alchemy.” Government regulation of the pharmaceutical industry is designed to protect consumers from unfounded scientific claims.
Born in the foothills of the Rocky Mountains, we’ve been growing some of the safest and most thoroughly tested medical cannabis on the market since 2016. Our state-of-the-art facility in Cremona, Alberta, was specifically designed to keep our plants happy, and alongside a meticulous process of harvesting and curing we ensure only the best product arrives at your door.
The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.[11]
The arrival of Epidiolex is unlikely to erase the unregulated CBD market, however. For one, Epidiolex has been studied only in connection with a small number of epileptic conditions. If and when Epidiolex makes its way to drug stores, it will be approved only for the treatment of Dravet Syndrome and Lennox-Gastaut Syndrome, two rare forms of catastrophic epilepsy. People like me, with comparatively mild Janz Syndrome, and people like Harper, with extremely rare conditions like CDKL5, may still be out of luck.

The question of whether heteromorphic sex chromosomes are indeed present is most conveniently answered if such chromosomes were clearly visible in a karyotype. Cannabis was one of the first plant species to be karyotyped; however, this was in a period when karyotype preparation was primitive by modern standards (see History of Cytogenetics). Heteromorphic sex chromosomes were reported to occur in staminate individuals of dioecious "Kentucky" hemp, but were not found in pistillate individuals of the same variety. Dioecious "Kentucky" hemp was assumed to use an XY mechanism. Heterosomes were not observed in analyzed individuals of monoecious "Kentucky" hemp, nor in an unidentified German cultivar. These varieties were assumed to have sex chromosome composition XX.[31] According to other researchers, no modern karyotype of Cannabis had been published as of 1996.[32] Proponents of the XY system state that Y chromosome is slightly larger than the X, but difficult to differentiate cytologically.[33]

Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner.[28][29] In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.[30] A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.[31]
The seeds are sown from mid-April to mid-May with grain drills to 4–6 cm sowing depth. Hemp needs less fertilizer than corn does. A total of 60–150 kg of nitrogen, 40–140 kg phosphorus (P2O5) and 75–200 kg of potassium [5] per acre for hemp fiber made before sowing and again later, maybe three to four weeks. When practiced, especially in France double use of fiber and seed fertilization with nitrogen doses up to 100 kg / ha rather low. Organic fertilizers such as manure can utilize industrial hemp well. Neither weeds nor crop protection measures are necessary.[52]
A rather thorough analysis of the scope of the illicit marijuana industry in Canada for 1998 is reported at www.rcmp-grc.gc.ca/html/drugsituation.htm#Marihuana and summarized in MacLeod (1999). At least 800 tonnes (t) of marijuana were grown in Canada in 1998, representing a harvest of 4.7 million flowering plants. More than 50% of the marijuana available in Canada is grown domestically. An average mature plant was estimated to produce 170 g of “marketable substance.” The value of the Canadian crop is uncertain, but has been estimated to be in the billions of dollars annually (Heading 1998; MacLeod 1999).

The Cannabis plant has a history of medicinal use dating back thousands of years across many cultures.[110] The Yanghai Tombs, a vast ancient cemetery (54 000 m2) situated in the Turfan district of the Xinjiang Uyghur Autonomous Region in northwest China, have revealed the 2700-year-old grave of a shaman. He is thought to have belonged to the Jushi culture recorded in the area centuries later in the Hanshu, Chap 96B.[111] Near the head and foot of the shaman was a large leather basket and wooden bowl filled with 789g of cannabis, superbly preserved by climatic and burial conditions. An international team demonstrated that this material contained tetrahydrocannabinol, the psychoactive component of cannabis. The cannabis was presumably employed by this culture as a medicinal or psychoactive agent, or an aid to divination. This is the oldest documentation of cannabis as a pharmacologically active agent.[112]
"Skunk" refers to several named strains of potent cannabis, grown through selective breeding and sometimes hydroponics. It is a cross-breed of Cannabis sativa and C. indica (although other strains of this mix exist in abundance). Skunk cannabis potency ranges usually from 6% to 15% and rarely as high as 20%. The average THC level in coffee shops in the Netherlands is about 18–19%.[242]
Salve, scusate la domanda banale. La titolazione al 10% indica 1000 mg. Questo vuole indicare che in ogni goccia ci sono 1000 mg di CBD? Io soffro di dolore cronico, fibromialgia, colon irritabile. Voglio acquistare la titolazione alta ma non comprendo perfettamente il dosaggio. Sulla base della vostra tabella patologia/dosaggio ho letto di usare 20 mg per circa 25 giorni..ma non capisco a questo punto come regolarmi. Mi sapreste indicare voi in gocce come devo utilizzarlo? Grazie
Henry Ford recognized the utility of hemp in early times. In advance of today’s automobile manufacturers, he constructed a car with certain components made of resin stiffened with hemp fiber (Fig. 19). Rather ironically in view of today’s parallel situation, Henry Ford’s hemp innovations in the 1920s occurred at a time of crisis for American farms, later to intensify with the depression. The need to produce new industrial markets for farm products led to a broad movement for scientific research in agriculture that came to be labeled “Farm Chemurgy,” that today is embodied in chemical applications of crop constituents.
38 states and Puerto Rico considered legislation related to industrial hemp in 2017. These bills ranged from clarifying existing laws to establishing new licensing requirements and programs.  At least 15 states enacted legislation in 2017 — Arkansas, Colorado, Florida, Hawaii, North Dakota, Nevada, New York, Oregon, South Carolina, Tennessee, Virginia, Washington, West Virginia, Wisconsin and Wyoming. Florida, Wisconsin and Nevada authorized new research or pilot programs. The governors of Arizona and New Mexico vetoed legislation, which would have established new research programs. 
Throughout his lifetime, George Washington cultivated hemp at Mount Vernon for industrial uses. The fibers from hemp held excellent properties for making rope and sail canvas. In addition, hemp fibers could be spun into thread for clothing or, as indicated in Mount Vernon records, used in repairing the large seine nets Washington used in his fishing operation along the Potomac.

So-called “pure hybrids,” while oxymoronic in name, indicate marijuana strains that are believed to offer a perfect blend or balance of sativa’s energizing and indica’s sedating effects. Other hybrid strains of cannabis tend to place the emphasis on one end of the spectrum or the other. These are called “sativa-dominant” or “indica-dominant,” accordingly.
As the range of Tweed and CraftGrow brands and products will change in the Shop over time, we recommend the Spectrum Cannabis brand when consistent access to the same product is important to you and your condition. If you have been taking a Tweed product that is no longer carried or available in our store, we have created a comprehensive table for you to explore alternative options. The goal of this table is to support treatment decisions with products most similar to what you have been taking, when a change is necessary.  Learn More
In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.

Another claim is that Mellon, Secretary of the Treasury and the wealthiest man in America at that time, had invested heavily in DuPont's new synthetic fiber, nylon, and believed[dubious – discuss] that the replacement of the traditional resource, hemp, was integral to the new product's success.[121][126][127][128][129][130][131][132] The company DuPont and many industrial historians dispute a link between nylon and hemp, nylon became immediately a scarce commodity.[clarification needed] Nylon had characteristics that could be used for toothbrushes (sold from 1938) and very thin nylon fiber could compete with silk and rayon in various textiles normally not produced from hemp fiber, such as very thin stockings for women.[125][133][134][135][136]
An observational study assessed the effectiveness of nabilone in advanced cancer patients who were experiencing pain and other symptoms (anorexia, depression, and anxiety). The researchers reported that patients who used nabilone experienced improved management of pain, nausea, anxiety, and distress when compared with untreated patients. Nabilone was also associated with a decreased use of opioids, nonsteroidal anti-inflammatory drugs, tricyclic antidepressants, gabapentin, dexamethasone, metoclopramide, and ondansetron.[56]
Prior to 2005's Hurricane Katrina, which caused widespread destruction and fatalities across New Orleans, Johnson had moved to California, and spent years there soaking up knowledge and culture around cannabis plants and the industry. After witnessing the pain and nausea his mother experienced during her treatment, Johnson decided to help bring the medicinal and economic value of cannabis back to his hometown, starting with hemp.
Fibres are obtained by subjecting the stalks to a series of operations—including retting, drying, and crushing—and a shaking process that completes separation from the woody portion, releasing the long, fairly straight fibre, or line. The fibre strands, usually over 1.8 metres (5.8 feet) long, are made of individual cylindrical cells with an irregular surface. The fibre, longer and less flexible than flax, is usually yellowish, greenish, or a dark brown or gray and, because it is not easily bleached to sufficiently light shades, is rarely dyed. It is strong and durable and is used for cordage—e.g., twine, yarn, rope, cable, and string—and for artificial sponges and such coarse fabrics as sacking (burlap) and canvas. In Italy some hemp receives special processing, producing whitish colour and attractive lustre, and is used to make fabric similar to linen.
The link provides additional information that may be useful or interesting and has no aliation to the promotion, sale and distribution of Medical Marijuana Inc. products. The link does not constitute an endorsement of these organizations by Medical Marijuana Inc. and none should be inferred. Please view our full Terms Of Use Agreement for more information and the terms and conditions governing your use of this site.

According to DSM-V criteria, 9% of those who are exposed to cannabis develop cannabis use disorder, compared to 20% for cocaine, 23% for alcohol and 68% for nicotine. Cannabis abuse disorder in the DSM-V involves a combination of DSM-IV criteria for cannabis abuse and dependence, plus the addition of craving, minus the criterion related to legal troubles.[110]

A 2015 review found that the use of high CBD-to-THC strains of cannabis showed significantly fewer positive symptoms such as delusions and hallucinations, better cognitive function and both lower risk for developing psychosis, as well as a later age of onset of the illness, compared to cannabis with low CBD-to-THC ratios.[267] A 2014 Cochrane review found that research was insufficient to determine the safety and efficacy to using cannabis to treat schizophrenia or psychosis.[268] As of 2017, the molecular mechanisms for the anti-inflammatory and possible pain relieving effects of cannabis are under preliminary research.[269]

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Based on world production of fibers in 1999, about 54.5% was synthetic (of which 60.3% was polyester), 42.9% was plant fiber (of which 78.5% was cotton), and 2.6% was wool (Karus 2000). In addition to cotton, flax is the only other significant plant fiber crop grown in temperate regions of the world (kenaf has received some enthusiastic backing in the southern US in recent years, but is most cheaply produced in India, Bangladesh, and China). Flax held 2.7% of the world plant fiber market in 1999, while hemp had only 0.3% (Karus 2000). Hemp fiber can potentially replace other biological fibers in many applications, but also, as noted below, can sometimes compete with minerals such as glass fiber and steel. As forests diminish, cultivation of annual plants as fiber sources is likely to increase. While crop residues like cereal straw will probably supply much of the need, specialty fiber plants such as hemp also have potential. The four conditions that will need to be met are (after Bolton 1995): (1) the material should be produced at a large enough scale; (2) the price should be low enough; (3) the fiber characteristics should be adequate for the end use; and (4) proven technology should be available for the processing of the new raw material. Of these criteria only point 3 is adequately met at this time for hemp in North America, but this is to be expected in a crop that has only begun to be cultivated after an absence of many years.
so you can just make up a new plant because it don’t get the user high? Hemp is Cannabis. PERIOD. The Farm Bill and No amount of silly dialog can create a new botanical entry. Hemp IS Cannabis. Cannabis Ruderalis, native to Russia, also called ditch weed….may be imported as Hemp but it IS Cannabis Ruderalis. The semantic name calling game is kept in motion because it serves the desires of those that profit on the confusion. Bottomline, there is Cannabis. Some Cannabis can be used to fight disease. Oligodenroglioma (in my case) and some of it can be used to alter one’s outlook……but it’s all Cannabis. Grow it in South Carolina and call it Hemp, I say God bless you, bring it to my lab and it comes out as cannabis and it’s going to be called Cannabis. Disclaimer, while I do have oligodendroglioma, I do not personally have a lab ;). M.
Another Israeli group postulated that the anti-inflammatory and immunosuppressive effects of CBD might make it a valuable adjunct in the treatment of acute graft-versus-host disease (GVHD) in patients who have undergone allogeneic hematopoietic stem cell transplantation. The authors investigated CBD 300 mg/d in addition to standard GVHD prophylaxis in 48 adult patients who had undergone transplantation predominantly for acute leukemia or myelodysplastic syndrome (NCT01385124 and NCT01596075).[21] The combination of CBD with standard GVHD prophylaxis was found to be safe. Compared with 101 historical controls treated with standard prophylaxis, patients who received CBD appeared to have a lower incidence of grade II to grade IV GVHD, suggesting that a randomized controlled trial (RCT) is warranted.
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.
Various strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC, and are known to contain other non-psychotropic cannabinoids.[61] Any psychoactive marijuana, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis. Non-psychoactive hemp (also commonly-termed industrial hemp), regardless of its CBD content, is any part of the cannabis plant, whether growing or not, containing a ∆-9 tetrahydrocannabinol concentration of no more than three-tenths of one percent (0.3%) on a dry weight basis.[62] Certain standards are required for legal growing, cultivating and producing the hemp plant. The Colorado Industrial Hemp Program registers growers of industrial hemp and samples crops to verify that the THC concentration does not exceed 0.3% on a dry weight basis.[62]
In the United States, the legality of medical marijuana varies in substantial ways from state to state. There are currently 29 US states with legal medical cannabis laws, as well as the District of Columbia. That leaves 21 states where medical marijuana is entirely prohibited. Marijuana cultivation, possession, and use in any form is illegal at the federal level.
The CBD oil needs to be taken twice a day everyday. The dosage depends on symptoms and it takes 30 days to awken your natural cannabis system after you begin taking the oil. I personally use Hemp works CBD oil in the 750 strength and only need 5 drops sublingual 2 times daily and results are many. Problem with oil and alz.patients is getting them to hold oil under tongue for 60 seconds. We have just began to get my dad on it. He too is in a nursing home in the state of florida and they cannot deny him any medication my mom has requested that he receive. If she is not their they are supposed to administer and she will call them to make sure he gets it. He is not 30 days into dosing yet so I don't have any results to speak of. I do know that since he has started he has had no more bladder infection and has not fallen in 3 weeks. That's a record for him so we will continue to monitor. Best of luck to you and a lot is going to depend on the state your mom is in and what the state laws are concerning her rights or the rights of whom has her medical power of attorney
Marijuana, also called pot, weed, ganja, mary jane, and a host of other nicknames, is made from the Cannabis plant, which has three species: Cannabis sativa; Cannabis indica and Cannabis ruderalis. The flowering plant, which can grow to 16 feet (5 meters) high, likely originated in the Central Asian steppe, near the Altai or Tian Shian Mountains, and was first cultivated in China and India, according to "Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential," (Routledge, 2002).
Hi Lauren I've just started today with 250mg cbd oil. I'm starting low to see what happens. I've nerve damage across buttocks from a laminectomy. I've not been able to sit for 5 years. I've recently started with a muscle spasm in my left buttock and the muscle above is painful. It is only the first day, also tried a cbd night time tea as well. Do change in muscle pain so tight on my left hand side. How long before felt it starting to work please. I'm trying not to expect changes straightaway. I also take 1100mg gabapentin and 30mg amitriptyline and I hate both of them - they both can cause muscle tightness affecting the nerve. Thank you Lyn
Animal studies have suggested a synergistic analgesic effect when cannabinoids are combined with opioids. The results from one pharmacokinetic interaction study have been reported. In this study, 21 patients with chronic pain were administered vaporized Cannabis along with sustained-release morphine or oxycodone for 5 days.[57] The patients who received vaporized Cannabis and sustained-release morphine had a statistically significant decrease in their mean pain score over the 5-day period; those who received vaporized Cannabis and oxycodone did not. These findings should be verified by further studies before recommendations favoring such an approach are warranted in general clinical practice.
The way I see it, the marriage of China’s position as the world’s supplier of hemp -- and its burgeoning semiconductor industry -- could be the key to China’s hegemony over the microchip industry. Semiconductors are traditionally made using silicon. Graphene semiconductors, however, could one day lead to computers that are a thousand times faster, consume significantly less power and are smaller than silicon semiconductors used in computer transistors. In application, graphene’s dwindling supply and costly manufacturing issues would still exist. Putting this all together, Mitlin’s research has sparked interest in the potential for hemp to create the next-generation semiconductor.

Hemp seeds contain virtually no THC, but THC contamination results from contact of the seeds with the resin secreted by the epidermal glands on the leaves and floral parts, and also by the failure to sift away all of the bracts (which have the highest concentration of THC of any parts of the plant) that cover the seeds. This results in small levels of THC appearing in hempseed oil and foods made with the seeds. Although most of the western hemp-growing world uses 0.3% THC as a maximum concentration for authorized cultivation of hemp plants, regulations in various countries allow only a much lower level of THC in human food products manufactured from the seeds. Currently, up to 10 ppm THC is permitted in seeds and oil products used for food purposes in Canada. In Germany, more stringent limits were set for food in 2000: 5 ppm in food oil, 0.005 ppm in beverages, and 0.15 ppm in all other foods. The US Drug Enforcement Administration published new regulations on hemp in the Federal Register on October 9th 2001 that in effect 4 months later would ban the food use of hemp in the US because any amount of THC would be unacceptable in foods (follow links at www.hempreport.com/). These proposals are currently being challenged by the hemp industry. Limits have been set because of concerns about possible toxicity and interference with drug tests (Grotenhermen et al. 1998). An extensive analysis of literature dealing with the toxicity of hemp is in Orr and Starodub (1999; see Geiwitz 2001 for an analysis). Because hemp food products are considered to have great economic potential, there is considerable pressure on the hemp industry in North America to reduce THC levels.

The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from organic hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.
Cannabis sativa L. subsp. sativa var. sativa is the variety grown for industrial use, while C. sativa subsp. indica generally has poor fiber quality and female buds from this variety are primarily used for recreational and medicinal purposes. The major differences between the two types of plants are the appearance, and the amount of Δ9-tetrahydrocannabinol (THC) secreted in a resinous mixture by epidermal hairs called glandular trichomes, although they can also be distinguished genetically.[55][57] Oilseed and fiber varieties of Cannabis approved for industrial hemp production produce only minute amounts of this psychoactive drug, not enough for any physical or psychological effects. Typically, hemp contains below 0.3% THC, while cultivars of Cannabis grown for medicinal or recreational use can contain anywhere from 2% to over 20%.[58]