In the United States, over three million people suffer from epilepsy – 470,000 of those people are children. Epilepsy is a disorder of the brain that causes seizures – of which there are over thirty different kinds, ranging from mild and infrequent to life-threatening. Not surprisingly, people with epilepsy face significant challenges – from the cost of healthcare to work limitations and social isolation.
There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.
The question of whether heteromorphic sex chromosomes are indeed present is most conveniently answered if such chromosomes were clearly visible in a karyotype. Cannabis was one of the first plant species to be karyotyped; however, this was in a period when karyotype preparation was primitive by modern standards (see History of Cytogenetics). Heteromorphic sex chromosomes were reported to occur in staminate individuals of dioecious "Kentucky" hemp, but were not found in pistillate individuals of the same variety. Dioecious "Kentucky" hemp was assumed to use an XY mechanism. Heterosomes were not observed in analyzed individuals of monoecious "Kentucky" hemp, nor in an unidentified German cultivar. These varieties were assumed to have sex chromosome composition XX. According to other researchers, no modern karyotype of Cannabis had been published as of 1996. Proponents of the XY system state that Y chromosome is slightly larger than the X, but difficult to differentiate cytologically.
Jump up ^ Hayakawa K, Mishima K, Hazekawa M, Sano K, Irie K, Orito K, Egawa T, Kitamura Y, Uchida N, Nishimura R, Egashira N, Iwasaki K, Fujiwara M (January 2008). "Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism". Brain Research. 1188: 157–64. doi:10.1016/j.brainres.2007.09.090. PMID 18021759.
The public forum sessions provided an overview of the Alternative Crop Research Act, including the legal parameters set within the bill, and the procedures that will guide development of the rules and regulations. Guest speakers included Brent Burchett, the director of the plant division from the Kentucky Department of Agriculture, and Mitch Yergert, retired director of the division of plant industry from the Colorado State Department of Agriculture.
μ-Opioid receptor agonists (opioids) (e.g., morphine, heroin, hydrocodone, oxycodone, opium, kratom) α2δ subunit-containing voltage-dependent calcium channels blockers (gabapentinoids) (e.g., gabapentin, pregabalin, phenibut) AMPA receptor antagonists (e.g., perampanel) CB1 receptor agonists (cannabinoids) (e.g., THC, cannabis) Dopamine receptor agonists (e.g., levodopa) Dopamine releasing agents (e.g., amphetamine, methamphetamine, MDMA, mephedrone) Dopamine reuptake inhibitors (e.g., cocaine, methylphenidate) GABAA receptor positive allosteric modulators (e.g., barbiturates, benzodiazepines, carbamates, ethanol (alcohol) (alcoholic drink), inhalants, nonbenzodiazepines, quinazolinones) GHB (sodium oxybate) and analogues Glucocorticoids (corticosteroids) (e.g., dexamethasone, prednisone) nACh receptor agonists (e.g., nicotine, tobacco, arecoline, areca nut) Nitric oxide prodrugs (e.g., alkyl nitrites (poppers)) NMDA receptor antagonists (e.g., DXM, ketamine, methoxetamine, nitrous oxide, phencyclidine, inhalants) Orexin receptor antagonists (e.g., suvorexant)
Cannabis is predominantly dioecious, having imperfect flowers, with staminate "male" and pistillate "female" flowers occurring on separate plants. "At a very early period the Chinese recognized the Cannabis plant as dioecious", and the (c. 3rd century BCE) Erya dictionary defined xi 枲 "male Cannabis" and fu 莩 (or ju 苴) "female Cannabis". Male flowers are normally borne on loose panicles, and female flowers are borne on racemes.
CBD in any capacity, other than products obtained and approved by a UNMC study or in a drug product approved by the FDA, remain illegal in Nebraska. The Attorney General re-issued a statement today of the law which said "Cannabidiol has been and continues to be included in Nebraska's Uniform Controlled Substances Act's legal definition of 'marijuana'"
There is great variation in Cannabis sativa, because of disruptive domestication for fiber, oilseed, and narcotic resin, and there are features that tend to distinguish these three cultigens (cultivated phases) from each other. Moreover, density of cultivation is used to accentuate certain architectural features. Figure 5 illustrates the divergent appearances of the basic agronomic categories of Cannabis in typical field configurations.
In the 1970s, President Nixon declared a “War on Drugs” and signed into law the Controlled Substances Act of 1970. This law established a set of banned drugs and created the Drug Enforcement Administration (DEA). It also unintentionally outlawed one of the world’s oldest domesticated crop, hemp. This not only led to the demise of hemp, but also an increased misconception of the plant.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary
Following an 1836–1840 travel in North Africa and the Middle East, French physician Jacques-Joseph Moreau wrote on the psychological effects of cannabis use; Moreau was a member of Paris' Club des Hashischins (founded in 1844). In 1842, Irish physician William Brooke O'Shaughnessy, who had studied the drug while working as a medical officer in Bengal with the East India company, brought a quantity of cannabis with him on his return to Britain, provoking renewed interest in the West. Examples of classic literature of the period featuring cannabis include Les paradis artificiels (1860) by Charles Baudelaire and The Hasheesh Eater (1857) by Fitz Hugh Ludlow.
The endocannabinoid system is believed to be centrally involved in the regulation of mood and the extinction of aversive memories. Animal studies have shown CBD to have anxiolytic properties. It was shown in rats that these anxiolytic properties are mediated through unknown mechanisms. Anxiolytic effects of CBD have been shown in several animal models.[53,54]
Of the 20 known amino acids, hemp supplies them all, including the essential ones the body can’t produce, known as EAAs. About 65 percent of the protein in hemp seeds is edestin, a globulin protein that aids in digestion, similar to the globulin found in human blood plasma, and hemp seeds are the only place they’re found. The other third is made up of the protein albumin.
Several of the cannabinoids are reputed to have medicinal potential: THC for glaucoma, spasticity from spinal injury or multiple sclerosis, pain, inflammation, insomnia, and asthma; CBD for some psychological problems. The Netherlands firm HortaPharm developed strains of Cannabis rich in particular cannabinoids. The British firm G.W. Pharmaceuticals acquired proprietary access to these for medicinal purposes, and is developing medicinal marijuana. In the US, NIH (National Institute of Health) has a program of research into medicinal marijuana, and has supplied a handful of individuals for years with maintenance samples for medical usage. The American Drug Enforcement Administration is hostile to the medicinal use of Cannabis, and for decades research on medicinal properties of Cannabis in the US has been in an extremely inhospitable climate, except for projects and researchers concerned with curbing drug abuse. Synthetic preparations of THC—dronabinol (Marinol®) and nabilone (Cesamet®)—are permitted in some cases, but are expensive and widely considered to be less effective than simply smoking preparations of marijuana. Relatively little material needs to be cultivated for medicinal purposes (Small 1971), although security considerations considerably inflate costs. The potential as a “new crop” for medicinal cannabinoid uses is therefore limited. However, the added-value potential in the form of proprietary drug derivatives and drug-delivery systems is huge. The medicinal efficacy of Cannabis is extremely controversial, and regrettably is often confounded with the issue of balancing harm and liberty concerning the proscriptions against recreational use of marijuana. This paper is principally concerned with the industrial uses of Cannabis. In this context, the chief significance of medicinal Cannabis is that, like the issue of recreational use, it has made it very difficult to rationally consider the development of industrial hemp in North America for purposes that everyone should agree are not harmful.
Cannabis was criminalized in various countries beginning in the 19th century. The British colonies of Mauritius banned cannabis in 1840 over concerns on its effect on Indian indentured workers; the same occurred in British Singapore in 1870. In the United States, the first restrictions on sale of cannabis came in 1906 (in District of Columbia). It was outlawed in Jamaica (then a British colony) in 1913, in South Africa in 1922, and in the United Kingdom and New Zealand in the 1920s. Canada criminalized cannabis in The Opium and Narcotic Drug Act, 1923, before any reports of the use of the drug in Canada, but eventually legalized its consumption for recreational and medicinal purposes in 2018.
Hemp paper are paper varieties consisting exclusively or to a large extent from pulp obtained from fibers of industrial hemp. The products are mainly specialty papers such as cigarette paper, banknotes and technical filter papers . Compared to wood pulp, hemp pulp offers a four to five times longer fibre, a significantly lower lignin fraction as well as a higher tear resistance and tensile strength. However, production costs are about four times higher than for paper from wood, so hemp paper could not be used for mass applications as printing, writing and packaging paper.
Unlike other Cannabis sativa varieties and hybrids, which are mostly grown for their chemically potent flowers (or 'buds'), hemp is also legally distinguished from marijuana in the US as containing less than 0.3% of the cannabinoid chemical THC — considered to be the most intoxicating, psychoactive component in cannabis plants, as well as a treatment option for certain serious illnesses.
No, as long as the plant is used correctly then no it’s not a bad thing. I’m sure there’s probably more good capability about that plant that people know or don’t know. No matter how it’s administered, as long as used properly it’s a good thing. It probably has more healing capabilities than people know about and since big Pharma or whoever it is out there discovered this, that’s probably why they made it illegal for all we know. Yes, I know there’s no money in cure which would hurt big Pharma but oh well! If they want to keep us away from the cure and keep us all sick, I say go for it anyway and go for the cure.
Retting is generally done in the field (Fig. 46, 47). This typically requires weeks. The windrows should be turned once or twice. If not turned, the stems close to the ground will remain green while the top ones are retted and turn brown. When the stalks have become sufficiently retted requires experience—the fibers should have turned golden or grayish in color, and should separate easily from the interior wood. Baling can be done with any kind of baler (Fig. 48). Stalks should have less than 15% moisture when baled, and should be allowed to dry to about 10% in storage. Bales must be stored indoors. Retted stalks are loosely held together, and for highest quality fiber applications need to be decorticated, scutched, hackled, and combed to remove the remaining pieces of stalks, broken fibers, and extraneous material. The equipment for this is rare in North America, and consequently use of domestically-produced fiber for high quality textile applications is extremely limited. However, as described above relatively crude fiber preparations also have applications.
It often takes 10 to 15 years for the industry associated with a new agricultural crop to mature. While it is true that foreign imports have been the basis for hemp products in North America for at least a decade, North American production is only 4 years of age in Canada, and farming of hemp in the US has not even begun. Viewed from this perspective, the hemp industry in North America is still very much in its infancy. Varieties of hemp specifically suited to given products and regions have only started to be developed in North America. There is considerable uncertainty regarding yields, costs of production, harvesting and processing equipment, product characteristics, foreign competition, governmental support, and the vagaries of the regulatory environment. Hemp is not presently a standard crop, and is likely to continue experiencing the risks inherent in a small niche market for some time. Hemp is currently a most uncertain crop, but has such a diversity of possible uses, is being promoted by extremely enthusiastic market developers, and attracts so much attention that it is likely to carve out a much larger share of the North American marketplace than its detractors are willing to concede.
Some manufacturers ship CBD products nationally, an illegal action which the FDA has not enforced in 2018, with CBD remaining as the subject of an FDA investigational new drug evaluation and is not considered legal as a dietary supplement or food ingredient as of November 2018. CBD is openly sold in head shops and health food stores in some states where such sales have not been explicitly legalized.
What is cannabis?Cannabis is a drug that comes from Indian hemp plants such as Cannabis sativa and Cannabis indica. The main active chemical in cannabis is THC (delta-9 tetrahydrocannabinol).Cannabis is a depressant drug. Depressant drugs do not necessarily make you feel depressed. Rather, they slow down the activity of the central nervous system and the messages going between the brain and the body. When large doses of cannabis are taken it may also produce hallucinogenic effects.For information on synthetic cannabinoids, see our "Legal high" facts page.Other namesCannabis is also known as grass, pot, hash, weed, reefer, dope, herb, mull, buddha, ganja, joint, stick, buckets, cones, skunk, hydro, yarndi, smoke and hooch.What does cannabis look like?Leaves from the cannabis plant are bright green and have a distinctive shape with five or seven leaflets. The flowering tops and upper leaves are covered in a sticky resin.Cannabis is used for the psychoactive (mind and mood-altering) effects of THC and other active ingredients. THC is the chemical in cannabis that makes you feel “high”.There are three main forms of psychoactive cannabis: marijuana, hashish and hash oil.Marijuana is the most common and least potent form of cannabis. Marijuana is the dried leaves and flowers of the plant.Hashish (“hash”) is dried cannabis resin, usually in the form of a small block. The concentration of THC in hashish is higher than in marijuana, producing stronger effects.Hash oil is a thick, oily liquid, golden brown to black in colour, which is extracted from cannabis. Hash oil is the strongest form of cannabis.How and why is it used?The different forms of cannabis are used in different ways:Marijuana is smoked in hand-rolled cigarettes (joints), or in a pipe (a bong).Hashish is usually added to tobacco and smoked, or baked and eaten in foods such as hash cookies.Hash oil is usually spread on the tip or paper of a cigarette and then smoked.Cannabis and hash can also be smoked in a vaporiser. Vaporisers heat cannabis to temperatures that release its active ingredients while minimising the toxins associated with burning.The THC in cannabis is absorbed into the bloodstream through the walls of the lungs (if smoked), or through the walls of the stomach and intestines (if eaten). The bloodstream carries the THC to the brain, producing the “high” effects. Drugs inhaled get into the bloodstream quicker than those eaten. This means that the effects of cannabis when smoked occur more rapidly than when eaten.Paper and textilesSome species of cannabis have few psychoactive effects. These plants are used to produce hemp fibre for use in paper, textiles and clothing.Medical usesCannabis has been used for medical purposes for many centuries. It has been reported that cannabis may be useful to help conditions such as:nausea and vomiting, particularly when associated with chemotherapywasting and severe weight loss, in people with HIV/AIDS, cancer, or anorexia nervosa, as it may be used as an appetite stimulantpain relief, for example in people with cancer and arthritisrelief from symptoms of some neurological disorders that involve muscle spasms, including multiple sclerosis and spinal cord injuryglaucomaepilepsyasthma.For more information, please click on the Australian Drug Foundation's DrugInfo Clearinghouse web site link below.
Today he sells numerous hemp-made items, from shoes to shirts, as well as a range of hemp-based health and medicinal products. After some productive networking at recent cannabis conventions, he's also in talks with Julian Marley to distribute his products around the country, and hopes to help bring a full-scale hemp festival — codename Hemp Hop — to New Orleans next year.
The vegetable oils have been classified by “iodine value” as drying (120–200), semi-drying (100–120), and non-drying (80–100), which is determined by the degree of saturation of the fatty acids present (Raie et al. 1995). Good coating materials prepared from vegetable oil depend on the nature and number of double bonds present in the fatty acids. Linseed oil, a drying oil, has a very high percentage of linolenic acid. Hempseed oil has been classified as a semi-drying oil, like soybean oil, and is therefore more suited to edible than industrial oil purposes. Nevertheless hemp oil has found applications in the past in paints, varnishes, sealants, lubricants for machinery, and printing inks. However, such industrial end uses are not presently feasible as the oil is considered too expensive (de Guzman 2001). Larger production volumes and lower prices may be possible, in which case hemp oil may find industrial uses similar to those of linseed (flax), soybean, and sunflower oils, which are presently used in paints, inks, solvents, binders, and in polymer plastics. Hemp shows a remarkable range of variation in oil constituents, and selection for oilseed cultivars with high content of valued industrial constituents is in progress.
I have digenerative disc disease/4 bulgin discs was taking 9---10mg hydrocodones a day... i started with 3 drops of 300mg and within 5 mins started feeling better than i have theses last 6 years or so... not only that, the inflamation has decrease substantially, i wake up with energy and have begun to work out again... if im making it seem like a miracle drug... its because it is... so the first week i took 3 drops twice a day... now 3 weeks in... im taking about 5 drops 3 times a day and zero pain pills... for the first time in years i have taken control of my life agin... not depending on doctor scripts/bills etc....
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