Do not use cannabis if you are pregnant or could become pregnant. There is some evidence that women who smoke cannabis during the time of conception or while pregnant may increase the risk of their child being born with birth defects. Pregnant women who continue to smoke cannabis are probably at greater risk of giving birth to low birthweight babies.
Cannabis is mostly used for recreation or as a medicinal drug, although it may also be used for spiritual purposes. In 2013, between 128 and 232 million people used cannabis (2.7% to 4.9% of the global population between the ages of 15 and 65). It is the most commonly used illegal drug both in the world and the United States. The countries with the highest use among adults as of 2018 are Zambia, the United States, Canada, and Nigeria. In 2016, 51% of people in the United States had ever used cannabis. About 12% had used it in the past year, and 7.3% had used it in the past month.
Cannabinoids may also contribute to pain modulation through an anti-inflammatory mechanism; a CB2 effect with cannabinoids acting on mast cell receptors to attenuate the release of inflammatory agents, such as histamine and serotonin, and on keratinocytes to enhance the release of analgesic opioids has been described.[45-47] One study reported that the efficacy of synthetic CB1- and CB2-receptor agonists were comparable with the efficacy of morphine in a murine model of tumor pain.
All other applicable federal and state regulations apply to the production of hemp products for human consumption and other uses (e.g. FDA, DPHHS). This list is not all inclusive and just includes examples of potential products from the pilot program. Pilot participants are allowed to harvest and process any hemp seed, oils, fiber, and hurd that they produce. They may process these items themselves or sell them for processing or use. All hemp produced must be processed before leaving Montana. Commercial production outside the Montana Hemp Pilot Program is not currently allowed under state or federal law.
A USDA analysis of hemp, “Industrial hemp in the United States: Status and market potential,” was issued in 2000, and is available at www.ers.usda.gov/publications/ages001e/index.htm. This is anonymously-authored, therefore presumably represents a corporate or “official” evaluation. The conclusion was that “US markets for hemp fiber (specialty textiles, paper, and composites) and seed (in food or crushed for oil) are, and will likely remain, small, thin markets. Uncertainty about longrun demand for hemp products and the potential for oversupply discounts the prospects for hemp as an economically viable alternative crop for American farmers.” Noting the oversupply of hempseeds associated with Canada’s 12,000 ha in 1999, the report concluded that the long term demand for hemp products is uncertain, and predicts that the hemp market in the US will likely remain small and limited. With respect to textiles, the report noted the lack of a thriving textile flax (linen) US industry (despite lack of legal barriers), so that it would seem unlikely that hemp could achieve a better market status. With respect to hemp oil, the report noted that hemp oil in food markets is limited by its short shelf life, the fact that it can not be used for frying, and the lack of US Food and Drug Administration approval as GRAS (“generally recognized as safe”). Moreover, summarizing four state analyses of hemp production (McNulty 1995, Ehrensing 1998, Kraenzel et al. 1998, Thompson et al. 1998), profitability seemed doubtful.
CBC is another lesser-known yet still crucial cannabinoid in marijuana, especially from a therapeutic perspective. While bereft of the psychoactive quality of THC (and to a lesser extent THCV), CBC is gaining popularity as an anxiety reducer. While research on cannabichromene lags behind others, there’s good reason to continue looking into its potential as a medicine.
Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps
Despite advances in pharmacologic and nonpharmacologic management, nausea and vomiting (N/V) remain distressing side effects for cancer patients and their families. Dronabinol, a synthetically produced delta-9-THC, was approved in the United States in 1986 as an antiemetic to be used in cancer chemotherapy. Nabilone, a synthetic derivative of delta-9-THC, was first approved in Canada in 1982 and is now also available in the United States. Both dronabinol and nabilone have been approved by the U.S. Food and Drug Administration (FDA)for the treatment of N/V associated with cancer chemotherapy in patients who have failed to respond to conventional antiemetic therapy. Numerous clinical trials and meta-analyses have shown that dronabinol and nabilone are effective in the treatment of N/V induced by chemotherapy.[25-28] The National Comprehensive Cancer Network Guidelines recommend cannabinoids as breakthrough treatment for chemotherapy-related N/V. The American Society for Clinical Oncology (ASCO) antiemetic guidelines updated in 2017 recommends that the FDA-approved cannabinoids, dronabinol or nabilone, be used to treat N/V that is resistant to standard antiemetic therapies.
Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity. But THC metabolites are stored in the fat cells of your body, building up over time. If you ever need to take a drug test, this could create an issue for you.
Cannabinoids, terpenoids, and other compounds are secreted by glandular trichomes that occur most abundantly on the floral calyxes and bracts of female plants. As a drug it usually comes in the form of dried flower buds (marijuana), resin (hashish), or various extracts collectively known as hashish oil. In the early 20th century, it became illegal in most of the world to cultivate or possess Cannabis for sale or personal use.
bNumber of patients treated plus number of patient controls may not equal number of patients enrolled; number of patients enrolled equals number of patients initially recruited/considered by the researchers who conducted a study; number of patients treated equals number of enrolled patients who were given the treatment being studied AND for whom results were reported.
In November 2015, Uttarakhand became the first state of India to legalize the cultivation of hemp for industrial purposes. Usage within the Hindu and Buddhist cultures of the Indian subcontinent is common, with many street vendors in India openly selling products infused with cannabis, and traditional medical practitioners in Sri Lanka selling products infused with cannabis for recreational purposes and well as for religious celebrations. It was criminalized in the Indian subcontinent by the Dutch and then the British. India and Sri Lanka have allowed cannabis to be taken in the context of traditional culture for recreational/celebratory purposes and also for medicinal purposes.
Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!
The U.S. hemp-derived CBD market alone is projected to reach $450 million by 2020, and China's cannabis market could grow to 100 billion yuan by 2022 (approximately $14.5 billion). Hemp is already interwoven into the futures of the automotive, construction, energy, environmental mediation and technology industries. Once fully utilized and legal, this plant could impact the global economic positionings of North America, China and Africa.
It’s easy to see why vaping has become such a popular method for consuming marijuana. The method is remarkably discrete and produces none of the telltale “weed smells” that often betray cannabis users. Vape pens and other hand-held devices are portable and convenient. They’re free of many of the harsh marijuana plant compounds that can harm your lung health, like tars. And companies are getting better at crafting high-quality, flavorful vape cartridges with a wide array of cannabinoid profiles.
One of the biggest players in this new industry is Medical Marijuana, Inc., a company formed in 2009 that operates out of Poway, California, just north of San Diego. It has played a leading role in the so-called Green Rush, as businesses have moved quickly to capitalize on the gradual legalization of marijuana for medical and recreational purposes by states across the country. The company’s spokesman, Andrew Hard, boasted that Medical Marijuana, Inc., “created the CBD industry and was first to market with CBD products.” Through its various subsidiaries, Medical Marijuana, Inc. sells some of the most recognizable products on the cannabis market— everything from Cibaderm CBD-infused shampoo to CanChew chewing gum. In 2014, the company generated $14.5 million in revenue.
Another Israeli group postulated that the anti-inflammatory and immunosuppressive effects of CBD might make it a valuable adjunct in the treatment of acute graft-versus-host disease (GVHD) in patients who have undergone allogeneic hematopoietic stem cell transplantation. The authors investigated CBD 300 mg/d in addition to standard GVHD prophylaxis in 48 adult patients who had undergone transplantation predominantly for acute leukemia or myelodysplastic syndrome (NCT01385124 and NCT01596075). The combination of CBD with standard GVHD prophylaxis was found to be safe. Compared with 101 historical controls treated with standard prophylaxis, patients who received CBD appeared to have a lower incidence of grade II to grade IV GVHD, suggesting that a randomized controlled trial (RCT) is warranted.
Millennia of selective breeding have resulted in varieties that display a wide range of traits; e.g. suited for a particular environments/latitudes, producing different ratios and compositions of terpenoids and cannabinoids (CBD, THC, CBG, CBC, CBN...etc.), fibre quality, oil/seed yield etc. Hemp grown for fiber is planted closely, resulting in tall, slender plants with long fibers.
Hemp is used in a variety of products we carry. The industrial hemp seed that is used in the products we carry today is not marijuana, although the two are from the same species (Cannabis Sativa). Hemp seeds are sterilized, removing any traces of THC – the mind-altering compound found in the drug. Industrial hemp can be grown with relatively little fertilizer and without the pesticides that have been known to pollute ground water and river systems.
Hi, Congrats on finishing chemo & radiation that’s awesome!! I wish you the best of luck!! I was actually wanting to know about dosage for cancer as well..My parents both have recently been diagnosed with cancer 4 months apart and are currently going thru chemo together. I have tried looking for the dosage info but can never find what i’m looking for..I want to try to help lesson the chemo side effects and hopefully kill some of the cancer cells. Can someone please help us?Thank You Christy
But recent activity in Washington has legislators in every aisle waving banners for hemp. So far, 20 states have stepped up to encourage industrial hemp production.5 On February 7, 2014, the 2013 Farm Bill6 was signed into law, legitimizing industrial hemp as distinct, and authorizing university and State departments of agriculture (where it’s legal) for research or pilot programs. On January 8, 2015, The Industrial Hemp Farming Act of 2015, S. 134, was introduced in the U.S. Senate.
Hemp hasn't always been on the wrong side of the authorities. The Puritans brought hemp with them to New England in 1645 and Europeans were growing it even earlier in Chile. George Washington planted hemp as one of several crops at his Mount Vernon estate. However, hemp's popularity waned in America as other plants used for textiles such as cotton and jute became more widely available. The U.S. Navy briefly campaigned for more hemp farming during World War II to supply ropes for ships. But the federal government continued restrictions on hemp after the war.
I strongly agree they really are greedy and money hungry. Isn’t it always funny how the big ones fall sooner or later? The government can’t have everything, there are just some things that belong to the people. Medicine plants in general have been around since the start of creation, and it looks like we’re just finding out which ones they are. Our forefathers know which ones they were and they knew how to use them but it’s been a forgotten skill some generations have forgotten since modern medicine took over. That’s not right. I saw some articles where the government was going to try to once again outlaw hemp and cannabis. I say if you really want some before it’s outlawed, grab up as much as you can and hide it somewhere good where no one but you can ever find it. I would highly recommend putting it in an airtight container with as many other airtight layers around it as possible. That way, it will never be found by anyone who’s not supposed to find it. The best advantage is to have enough handy to take care of yourself for life while everyone not in on ditching big Pharma is dying. If hamper and cannabis are outlawed, only the elite will be the ones still standing in the end
The public forum sessions provided an overview of the Alternative Crop Research Act, including the legal parameters set within the bill, and the procedures that will guide development of the rules and regulations. Guest speakers included Brent Burchett, the director of the plant division from the Kentucky Department of Agriculture, and Mitch Yergert, retired director of the division of plant industry from the Colorado State Department of Agriculture.
The high absorbency of hemp hurds has led to their occasional use as an absorbent for oil and waste spill cleanup. Hemp as an industrial absorbent has generated some interest in Alberta, for use in land reclamation in the oil and gas industry. Because hemp hurds are a costly product, it is likely that animal bedding will remain the most important application.
An alternative to the gateway hypothesis is the common liability to addiction (CLA) theory. It states that some individuals are, for various reasons, willing to try multiple recreational substances. The "gateway" drugs are merely those that are (usually) available at an earlier age than the harder drugs. Researchers have noted in an extensive review that it is dangerous to present the sequence of events described in gateway "theory" in causative terms as this hinders both research and intervention.
Not until the end of the 20th century was the specific mechanism of action of THC at the neuronal level studied. Researchers have subsequently confirmed that THC exerts its most prominent effects via its actions on two types of cannabinoid receptors, the CB1 receptor and the CB2 receptor, both of which are G protein-coupled receptors. The CB1 receptor is found primarily in the brain as well as in some peripheral tissues, and the CB2 receptor is found primarily in peripheral tissues, but is also expressed in neuroglial cells. THC appears to alter mood and cognition through its agonist actions on the CB1 receptors, which inhibit a secondary messenger system (adenylate cyclase) in a dose-dependent manner. These actions can be blocked by the selective CB1 receptor antagonist rimonabant (SR141716), which has been shown in clinical trials to be an effective treatment for smoking cessation, weight loss, and as a means of controlling or reducing metabolic syndrome risk factors. However, due to the dysphoric effect of CB1 receptor antagonists, this drug is often discontinued due to these side effects.
A short-term Advisory Board has been appointed to serve through the development of the rules and regulations. The rules and regulations themselves will identify the guidelines for formation of the Advisory Board, so upon adoption of the rules and regulations an Advisory Board will be created which will continue on a regular basis beyond that point.
Cannabis has an ancient history of ritual use and is found in pharmacological cults around the world. Hemp seeds discovered by archaeologists at Pazyryk suggest early ceremonial practices like eating by the Scythians occurred during the 5th to 2nd century BC, confirming previous historical reports by Herodotus. It was used by Muslims in various Sufi orders as early as the Mamluk period, for example by the Qalandars. Smoking pipes uncovered in Ethiopia and carbon-dated to around c. AD 1320 were found to have traces of cannabis.
I had come to meet Dr. Angel Hernandez, the director of the hospital’s pediatric epilepsy program. A trail of wall-mounted signs led me to the pediatric neurology ward, a bright and airy space with flat-screen TVs running cartoons nonstop. Decorative kites were strung up in the corridors, and rainbow curtains lined the windows. Some of the kids in the waiting area that morning were alert and awake, others groggy. Some were strapped into special strollers designed for children with mobility problems, and some had shaven heads and healing scars. Hernandez came out to greet me, and I was surprised he recognized me after what felt like a very long time. He had diagnosed me with epilepsy in 2004 and treated me for several years.
In December 2013, Uruguay became the first country to legalize growing, sale and use of cannabis. After a long delay in implementing the retail component of the law, in 2017 sixteen pharmacies were authorized to sell cannabis commercially. On June 19, 2018, the Canadian Senate passed a bill and the Prime Minister announced the effective legalization date as October 17, 2018. Canada is the second nation to legalize the drug.
Separate levels of evidence scores are assigned to qualifying human studies on the basis of statistical strength of the study design and scientific strength of the treatment outcomes (i.e., endpoints) measured. The resulting two scores are then combined to produce an overall score. An overall level of evidence score cannot be assigned to cannabinoids because there has been insufficient clinical research. For an explanation of possible scores and additional information about levels of evidence analysis of CAM treatments for people with cancer, refer to Levels of Evidence for Human Studies of Integrative, Alternative, and Complementary Therapies.
I totally agree. The greed of the pharmaceutical with their lobbyist to stop the government from making it a schedule III drug so much more research can be done. They do not care about the people, just money. We the people must rise up and let our government know, we care more about our friends and family than the money they give, to you congress men/women and senators get, and we VOTE. The only power we have is writing or calling congress men/women and senators, huge rallies and each and every ones VOTE. They would rather stay in office, than even receive big monies from big pharm for their campaigns. VOTES will win over.
Marijuana, also called pot, weed, ganja, mary jane, and a host of other nicknames, is made from the Cannabis plant, which has three species: Cannabis sativa; Cannabis indica and Cannabis ruderalis. The flowering plant, which can grow to 16 feet (5 meters) high, likely originated in the Central Asian steppe, near the Altai or Tian Shian Mountains, and was first cultivated in China and India, according to "Cannabis and Cannabinoids: Pharmacology, Toxicology and Therapeutic Potential," (Routledge, 2002).
Henry Ford recognized the utility of hemp in early times. In advance of today’s automobile manufacturers, he constructed a car with certain components made of resin stiffened with hemp fiber (Fig. 19). Rather ironically in view of today’s parallel situation, Henry Ford’s hemp innovations in the 1920s occurred at a time of crisis for American farms, later to intensify with the depression. The need to produce new industrial markets for farm products led to a broad movement for scientific research in agriculture that came to be labeled “Farm Chemurgy,” that today is embodied in chemical applications of crop constituents.
Hi…I read your statement about hemp being a cream that takes pain away. Living in Oregon there’s no talk about “hemp” but I don’t doubt your experience with it..and I’m wondering where you found it..so that maybe I can get a jar of it and see if it would help my aches and pains….I would really appreciate your response…and thanks for your “reply” that motivated me to write to you..
The Cannabis plant has a history of medicinal use dating back thousands of years across many cultures. The Yanghai Tombs, a vast ancient cemetery (54 000 m2) situated in the Turfan district of the Xinjiang Uyghur Autonomous Region in northwest China, have revealed the 2700-year-old grave of a shaman. He is thought to have belonged to the Jushi culture recorded in the area centuries later in the Hanshu, Chap 96B. Near the head and foot of the shaman was a large leather basket and wooden bowl filled with 789g of cannabis, superbly preserved by climatic and burial conditions. An international team demonstrated that this material contained tetrahydrocannabinol, the psychoactive component of cannabis. The cannabis was presumably employed by this culture as a medicinal or psychoactive agent, or an aid to divination. This is the oldest documentation of cannabis as a pharmacologically active agent.
Reproduced with kind permission from the Australian Drug Foundation. References Australian Drug Foundation. Cannabis Facts. Last updated 25 Jan 2012. http://www.druginfo.adf.org.au/drug-facts/cannabis (accessed Jan 2013). Australian Drug Foundation (ADF) Vision: Healthy People, Strong Communities. Mission: Working together to prevent alcohol and other drug problems in communities.Related ArticlesCannabis psychosisUse of cannabis can cause a condition called drug-induced psychosis. Cannabis useCannabis can affect your physical and mental health with heavy cannabis use potentially causing psycCannabis: tolerance and dependenceAfter prolonged use, cannabis is addictive and people using cannabis regularly develop dependence anCannabis: withdrawal and treatmentIf a dependent person stops taking cannabis, they may experience withdrawal symptoms. Cannabis/marijuana: what are the effects?The effect of cannabis on a person depends on many factors including their size, weight and health aAdvertisement
The scientific debate regarding taxonomy has had little effect on the terminology in widespread use among cultivators and users of drug-type Cannabis. Cannabis aficionados recognize three distinct types based on such factors as morphology, native range, aroma, and subjective psychoactive characteristics. Sativa is the most widespread variety, which is usually tall, laxly branched, and found in warm lowland regions. Indica designates shorter, bushier plants adapted to cooler climates and highland environments. Ruderalis is the informal name for the short plants that grow wild in Europe and Central Asia.